SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3d6t LEUCINE-RICH REPEAT
SERINE/THREONINE-PRO
TEIN KINASE 2
(Homo
sapiens) 		4 / 7 LYS B1468
ILE B1482
LYS B1439
TYR B1419
 None
 1.18A 3eteD-3d6tB:
undetectable
3eteF-3d6tB:
undetectable		 3eteD-3d6tB:
15.94
3eteF-3d6tB:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3d6t LEUCINE-RICH REPEAT
SERINE/THREONINE-PRO
TEIN KINASE 2
(Homo
sapiens) 		4 / 7 ASP B1394
PHE B1395
GLY B1397
THR B1348
 None
 1.16A 3vnsA-3d6tB:
undetectable		 3vnsA-3d6tB:
15.84