SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3d6w METHYL-ACCEPTING/DNA
RESPONSE REGULATOR
(Bacillus
cereus) 		4 / 6 VAL A 110
HIS A 147
LEU A 112
LEU A 129
 None
 1.08A 5hrqB-3d6wA:
undetectable
5hrqI-3d6wA:
undetectable
5hrqJ-3d6wA:
undetectable		 5hrqB-3d6wA:
17.98
5hrqI-3d6wA:
13.48
5hrqJ-3d6wA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3d6w METHYL-ACCEPTING/DNA
RESPONSE REGULATOR
(Bacillus
cereus) 		5 / 9 LEU A 157
PHE A 154
GLU A 153
LEU A 151
VAL A 110
 None
 1.25A 6ftpA-3d6wA:
undetectable
6ftpB-3d6wA:
undetectable		 6ftpA-3d6wA:
19.64
6ftpB-3d6wA:
17.00