SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDB_A_NPSA1591_1 (SERUM ALBUMIN)	3d6x	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Campylobacter jejuni)	4 / 8	PHE A 89 LEU A 139 PHE A 123 GLY A 68	None	0.79A	2vdbA-3d6xA: undetectable	2vdbA-3d6xA: 15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRZ_B_ACTB1463_0 (DEOXYRIBODIPYRIMIDIN E PHOTOLYASE)	3d6x	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Campylobacter jejuni)	4 / 7	VAL A 70 ILE A 23 GLY A 68 THR A 67	None	0.68A	2xrzB-3d6xA: undetectable	2xrzB-3d6xA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_2 (ANDROGEN RECEPTOR)	3d6x	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Campylobacter jejuni)	4 / 6	ASN A 116 LEU A 71 MET A 120 VAL A 87	None	1.07A	4okbA-3d6xA: undetectable	4okbA-3d6xA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_A_SAMA301_1 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	3d6x	(3R)-HYDROXYMYRISTOY L-[ACYL-CARRIER-PROT EIN] DEHYDRATASE (Campylobacter jejuni)	3 / 3	GLY A 104 ASP A 105 ASN A 132	None	0.47A	5jglA-3d6xA: undetectable	5jglA-3d6xA: 17.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VDB_A_NPSA1591_1","SERUM ALBUMIN","3d6x","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Campylobacter jejuni",4,"PHE A  89;LEU A 139;PHE A 123;GLY A  68","None","0.79A","2vdbA-3d6xA:undetectable","2vdbA-3d6xA:15.59"],["2XRZ_B_ACTB1463_0","DEOXYRIBODIPYRIMIDINE PHOTOLYASE","3d6x","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Campylobacter jejuni",4,"VAL A  70;ILE A  23;GLY A  68;THR A  67","None","0.68A","2xrzB-3d6xA:undetectable","2xrzB-3d6xA:17.34"],["4OKB_A_198A1002_2","ANDROGEN RECEPTOR","3d6x","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Campylobacter jejuni",4,"ASN A 116;LEU A  71;MET A 120;VAL A  87","None","1.07A","4okbA-3d6xA:undetectable","4okbA-3d6xA:20.59"],["5JGL_A_SAMA301_1","UBIE\/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE","3d6x","(3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE","Campylobacter jejuni",3,"GLY A 104;ASP A 105;ASN A 132","None","0.47A","5jglA-3d6xA:undetectable","5jglA-3d6xA:17.48"]]