SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 11 LEU A 101
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.92A 1c6yA-3d79A:
undetectable		 1c6yA-3d79A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.00A 1c6zB-3d79A:
undetectable		 1c6zB-3d79A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 10 LEU A 101
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.96A 1hsgA-3d79A:
undetectable		 1hsgA-3d79A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.04A 1hsgB-3d79A:
undetectable		 1hsgB-3d79A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.08A 2f8gB-3d79A:
undetectable		 2f8gB-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 11 ALA A  96
VAL A 106
ILE A 111
ALA A 136
ILE A 100
 None
 1.03A 2idwA-3d79A:
undetectable		 2idwA-3d79A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ALA A 136
ILE A 100
 None
 1.28A 2nmzB-3d79A:
undetectable		 2nmzB-3d79A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.06A 2o4lB-3d79A:
undetectable		 2o4lB-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.14A 2q63A-3d79A:
undetectable		 2q63A-3d79A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.10A 2q64B-3d79A:
undetectable		 2q64B-3d79A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.08A 2qakA-3d79A:
undetectable		 2qakA-3d79A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 11 ILE A 111
ILE A 118
ALA A 140
ALA A 155
VAL A 106
 None
 1.12A 2qhfA-3d79A:
undetectable		 2qhfA-3d79A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.10A 3bvbA-3d79A:
undetectable		 3bvbA-3d79A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ILE A 100
 None
 1.04A 3cyxA-3d79A:
undetectable		 3cyxA-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 10 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.97A 3ekpD-3d79A:
undetectable		 3ekpD-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 10 LEU A 101
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.99A 3em3B-3d79A:
undetectable		 3em3B-3d79A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		4 / 4 LEU A 101
ALA A 136
VAL A 126
PRO A 134
 None
 0.80A 3gv1B-3d79A:
undetectable		 3gv1B-3d79A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.03A 3jw2B-3d79A:
undetectable		 3jw2B-3d79A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.12A 3k4vB-3d79A:
undetectable		 3k4vB-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.09A 3nu5A-3d79A:
undetectable		 3nu5A-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 10 LEU A 101
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.99A 3oxwB-3d79A:
undetectable		 3oxwB-3d79A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.04A 3oxxA-3d79A:
undetectable		 3oxxA-3d79A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ILE A 100
 None
 1.04A 3oxxA-3d79A:
undetectable		 3oxxA-3d79A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ILE A 100
 None
 1.04A 3oxxC-3d79A:
undetectable		 3oxxC-3d79A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		4 / 5 VAL A 158
ILE A  61
MET A  33
ARG A 163
 None
 1.45A 3pyyB-3d79A:
undetectable		 3pyyB-3d79A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ILE A 100
 None
 0.98A 3tkgB-3d79A:
undetectable		 3tkgB-3d79A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 0.96A 3tkgD-3d79A:
undetectable		 3tkgD-3d79A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.04A 3tkwB-3d79A:
undetectable		 3tkwB-3d79A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.08A 3tl9B-3d79A:
undetectable		 3tl9B-3d79A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
ALA A  96
ASP A  93
VAL A 106
ILE A 111
ILE A 100
 None
 1.48A 4jecA-3d79A:
undetectable		 4jecA-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.02A 4jecA-3d79A:
undetectable		 4jecA-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.03A 4jecB-3d79A:
undetectable		 4jecB-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 LEU A 101
GLY A  95
ALA A  96
ILE A 111
ILE A 100
 None
 1.05A 4jecB-3d79A:
undetectable		 4jecB-3d79A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.02A 4njvD-3d79A:
undetectable		 4njvD-3d79A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		3 / 3 ALA A  73
ASN A  76
LEU A  77
 None
 0.47A 5i1nC-3d79A:
undetectable		 5i1nC-3d79A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 VAL A  54
ILE A 166
ILE A  67
ILE A 137
PHE A  25
 None
 0.99A 5mueA-3d79A:
undetectable		 5mueA-3d79A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 10 PRO A 134
TYR A  75
ILE A  72
ILE A 137
ILE A  61
 None
 1.10A 5murE-3d79A:
undetectable		 5murE-3d79A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		4 / 5 ASN A  76
ASP A  79
SER A  78
ARG A 133
 None
 1.50A 5w4zA-3d79A:
undetectable		 5w4zA-3d79A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		5 / 12 GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.03A 6dh3B-3d79A:
undetectable		 6dh3B-3d79A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3d79 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0734
(Pyrococcus
horikoshii) 		6 / 12 LEU A 101
GLY A  95
ALA A  96
VAL A 106
ILE A 111
ILE A 100
 None
 1.07A 6dilB-3d79A:
undetectable		 6dilB-3d79A:
20.11