SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R5L_A_VIVA301_0 (PROTEIN (ALPHA-TOCOPHEROL TRANSFER PROTEIN))	3d7i	CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (Methanocaldococc us jannaschii)	5 / 12	ILE A 73 ILE A 48 VAL A 51 ILE A 100 ILE A 78	None	1.21A	1r5lA-3d7iA: undetectable	1r5lA-3d7iA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XRZ_B_ACTB1463_0 (DEOXYRIBODIPYRIMIDIN E PHOTOLYASE)	3d7i	CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (Methanocaldococc us jannaschii)	4 / 7	VAL A 81 ILE A 48 ALA A 52 VAL A 85	None	0.66A	2xrzB-3d7iA: undetectable	2xrzB-3d7iA: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XTA_A_DIFA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3d7i	CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (Methanocaldococc us jannaschii)	5 / 9	SER A 66 ALA A 67 LEU A 104 LEU A 101 ILE A 60	None	1.45A	4xtaA-3d7iA: undetectable	4xtaA-3d7iA: 20.96