SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		3 / 3 GLU A  97
GLU A  58
LEU A 111
 None
 0.71A 1v8bA-3d7jA:
undetectable		 1v8bA-3d7jA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		5 / 10 HIS A  14
HIS A  28
THR A  84
GLU A  85
GLU A 120
 None
 0.87A 2dttD-3d7jA:
14.4
2dttF-3d7jA:
14.4		 2dttD-3d7jA:
24.38
2dttF-3d7jA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		4 / 6 HIS A 100
ARG A  98
GLY A 102
LYS A 101
 None
 1.17A 2i30A-3d7jA:
undetectable		 2i30A-3d7jA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		4 / 6 LEU A  66
ARG A  94
ILE A  91
ILE A   4
 None
 0.62A 2xkwB-3d7jA:
undetectable		 2xkwB-3d7jA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		5 / 12 ALA A  36
LEU A 104
GLY A 113
VAL A  50
VAL A  49
 None
 0.91A 3rukB-3d7jA:
undetectable		 3rukB-3d7jA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		5 / 12 ALA A  36
LEU A 104
GLY A 113
VAL A  50
VAL A  49
 None
 0.92A 4nkvB-3d7jA:
undetectable		 4nkvB-3d7jA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3d7j UNCHARACTERIZED
PROTEIN SCO6650
(Streptomyces
coelicolor) 		5 / 10 ASP A  51
VAL A  50
VAL A  49
THR A  37
ALA A  36
 None
 1.26A 4yhaB-3d7jA:
undetectable		 4yhaB-3d7jA:
18.41