SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 5 LEU A  93
GLY A  88
ILE A  43
ILE A  46
 None
 0.81A 2q9rA-3d7lA:
undetectable		 2q9rA-3d7lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 7 LEU A   5
VAL A  60
THR A 110
VAL A 179
 None
 1.06A 2zaxA-3d7lA:
undetectable		 2zaxA-3d7lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 7 ALA A   8
SER A  33
THR A  28
VAL A  26
 None
 0.97A 3d2tA-3d7lA:
undetectable		 3d2tA-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 6 ALA A   8
SER A  33
THR A  28
VAL A  26
 None
 0.98A 3d2tB-3d7lA:
undetectable		 3d2tB-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 11 GLY A  30
ALA A  29
ASP A  35
ILE A  27
ILE A  59
 None
 1.10A 3ebzB-3d7lA:
undetectable		 3ebzB-3d7lA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 7 LEU A   5
VAL A  60
THR A 110
VAL A 179
 None
 1.04A 3fwgB-3d7lA:
undetectable		 3fwgB-3d7lA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 7 LEU A   5
VAL A  60
THR A 110
VAL A 179
 None
 1.04A 3fwiA-3d7lA:
undetectable		 3fwiA-3d7lA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
GLY A 112
ASN A 129
ILE A 113
 None
 1.26A 3k13A-3d7lA:
2.4		 3k13A-3d7lA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
GLY A 112
ASN A 129
ILE A 113
 None
 1.26A 3k13B-3d7lA:
2.1		 3k13B-3d7lA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
GLY A 112
ASN A 129
ILE A 113
 None
 1.25A 3k13C-3d7lA:
undetectable		 3k13C-3d7lA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 112
ALA A 176
GLU A 159
THR A  11
LEU A  12
 None
 1.03A 3p2kB-3d7lA:
3.7		 3p2kB-3d7lA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 10 ILE A   6
ALA A  62
SER A 106
ILE A 149
ILE A  59
 None
 1.25A 3qgtA-3d7lA:
undetectable		 3qgtA-3d7lA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A  30
ALA A  29
ASP A  35
ILE A  27
ILE A  59
 None
 1.09A 3s56A-3d7lA:
undetectable		 3s56A-3d7lA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 9 PHE A 171
VAL A 156
ASN A 155
GLY A 112
PHE A  68
 None
 1.20A 3t3rC-3d7lA:
undetectable		 3t3rC-3d7lA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A  97
LEU A 101
ILE A   6
ASN A  92
LEU A 109
 None
 1.09A 4fr0A-3d7lA:
4.4		 4fr0A-3d7lA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 10 ILE A 147
ALA A 140
PHE A 107
ILE A  98
THR A 192
 None
 1.26A 4g8zX-3d7lA:
undetectable		 4g8zX-3d7lA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 7 LEU A   5
THR A 110
THR A 108
VAL A 152
 None
 0.78A 4ik7A-3d7lA:
undetectable		 4ik7A-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		4 / 8 LEU A   5
THR A 110
THR A 108
VAL A 152
 None
 0.72A 4ik7B-3d7lA:
undetectable		 4ik7B-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 10 ILE A 147
ALA A 140
PHE A 107
ILE A  98
THR A 192
 None
 1.27A 4km0A-3d7lA:
undetectable		 4km0A-3d7lA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 11 GLY A  89
GLY A  88
LEU A 109
VAL A 132
ILE A  40
 None
 1.06A 4pghA-3d7lA:
5.5		 4pghA-3d7lA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A   8
GLY A  13
LYS A  17
LEU A 157
GLU A 158
 None
 1.18A 5nwuA-3d7lA:
undetectable		 5nwuA-3d7lA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
LEU A 157
GLY A 112
ILE A 113
 None
 1.12A 5vooE-3d7lA:
3.4		 5vooE-3d7lA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
LEU A 157
GLY A 112
ILE A 113
 None
 1.10A 5vooF-3d7lA:
2.5		 5vooF-3d7lA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 122
VAL A 174
LEU A 157
GLY A 112
ILE A 113
 None
 1.11A 5vopB-3d7lA:
2.1		 5vopB-3d7lA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3d7l LIN1944 PROTEIN
(Listeria
innocua) 		5 / 12 ILE A  40
LEU A  93
GLY A  34
ALA A  29
LEU A   4
 None
 1.03A 5zwrA-3d7lA:
undetectable		 5zwrA-3d7lA:
19.49