SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 10 LEU A 152
LEU A  48
LEU A  73
ALA A  69
LEU A  75
 None
 1.27A 1ie4A-3d8nA:
undetectable
1ie4C-3d8nA:
undetectable		 1ie4A-3d8nA:
21.77
1ie4C-3d8nA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 5 LEU A 179
GLY A 214
PRO A 228
ALA A 210
 None
 0.87A 2aohA-3d8nA:
undetectable		 2aohA-3d8nA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 ALA A  88
VAL A 107
GLY A 108
GLY A 110
LEU A  97
ALA A  94
 None
 1.33A 2z0yA-3d8nA:
2.8		 2z0yA-3d8nA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 ALA A  88
VAL A 107
GLY A 108
GLY A 110
LEU A  97
ALA A  94
 None
 1.23A 2z0yB-3d8nA:
undetectable		 2z0yB-3d8nA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 5 PRO A  37
THR A  59
VAL A  61
GLY A  62
 None
UP3  A 944 (-4.2A)
UP3  A 944 ( 3.8A)
None
 1.01A 3elzA-3d8nA:
undetectable		 3elzA-3d8nA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 5 LEU A 150
GLN A  50
LEU A  48
GLU A  47
 None
 1.13A 3h5gA-3d8nA:
undetectable
3h5gB-3d8nA:
undetectable		 3h5gA-3d8nA:
9.27
3h5gB-3d8nA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 PHE A 191
LEU A 221
ALA A 203
THR A 206
VAL A 226
 None
 1.01A 3rukA-3d8nA:
undetectable		 3rukA-3d8nA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 6 SER A 114
VAL A 216
THR A  58
THR A  59
 None
None
None
UP3  A 944 (-4.2A)
 1.11A 3tneA-3d8nA:
undetectable		 3tneA-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 8 LEU A 152
TYR A  41
LEU A  75
LEU A  77
 None
 1.02A 4l1xA-3d8nA:
undetectable		 4l1xA-3d8nA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 9 ALA A  88
LYS A  98
GLU A  99
PHE A  55
LEU A  66
 None
 1.27A 4la0B-3d8nA:
undetectable		 4la0B-3d8nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 ALA A  93
GLY A 108
GLY A 110
ASP A 109
ALA A  88
 None
 0.96A 4lg1A-3d8nA:
2.6		 4lg1A-3d8nA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 12 ALA A  93
GLY A 108
GLY A 110
ASP A 109
ALA A  88
 None
 0.97A 4lg1C-3d8nA:
undetectable		 4lg1C-3d8nA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 11 ARG A  89
LEU A  56
GLU A 144
LEU A 142
LEU A 119
 None
 1.18A 4wg0J-3d8nA:
undetectable
4wg0K-3d8nA:
undetectable
4wg0L-3d8nA:
undetectable		 4wg0J-3d8nA:
4.78
4wg0K-3d8nA:
4.78
4wg0L-3d8nA:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 167
ALA A   4
ALA A 210
LEU A 190
ALA A   6
 None
 0.94A 4z90A-3d8nA:
undetectable
4z90B-3d8nA:
undetectable
4z90C-3d8nA:
undetectable
4z90D-3d8nA:
undetectable
4z90E-3d8nA:
undetectable		 4z90A-3d8nA:
21.05
4z90B-3d8nA:
21.05
4z90C-3d8nA:
21.05
4z90D-3d8nA:
21.05
4z90E-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 167
ALA A   4
LEU A 204
ALA A 210
ALA A   6
 None
 1.08A 4z90A-3d8nA:
undetectable
4z90B-3d8nA:
undetectable
4z90C-3d8nA:
undetectable
4z90D-3d8nA:
undetectable
4z90E-3d8nA:
undetectable		 4z90A-3d8nA:
21.05
4z90B-3d8nA:
21.05
4z90C-3d8nA:
21.05
4z90D-3d8nA:
21.05
4z90E-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 167
ALA A   6
LEU A 179
LEU A 204
LEU A 200
 None
 1.13A 4z90A-3d8nA:
undetectable
4z90B-3d8nA:
undetectable
4z90C-3d8nA:
undetectable
4z90D-3d8nA:
undetectable
4z90E-3d8nA:
undetectable		 4z90A-3d8nA:
21.05
4z90B-3d8nA:
21.05
4z90C-3d8nA:
21.05
4z90D-3d8nA:
21.05
4z90E-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 179
LEU A 204
LEU A 200
LEU A 167
ALA A   6
 None
 1.13A 4z90A-3d8nA:
undetectable
4z90B-3d8nA:
undetectable
4z90C-3d8nA:
undetectable
4z90D-3d8nA:
undetectable
4z90E-3d8nA:
undetectable		 4z90A-3d8nA:
21.05
4z90B-3d8nA:
21.05
4z90C-3d8nA:
21.05
4z90D-3d8nA:
21.05
4z90E-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 8 LEU A 200
LEU A 167
ALA A   6
LEU A 179
LEU A 204
 None
 1.11A 4z90A-3d8nA:
undetectable
4z90B-3d8nA:
undetectable
4z90C-3d8nA:
undetectable
4z90D-3d8nA:
undetectable
4z90E-3d8nA:
undetectable		 4z90A-3d8nA:
21.05
4z90B-3d8nA:
21.05
4z90C-3d8nA:
21.05
4z90D-3d8nA:
21.05
4z90E-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		5 / 7 LEU A 167
ALA A   4
ALA A 210
LEU A 190
ALA A   6
 None
 0.94A 4z90F-3d8nA:
undetectable
4z90G-3d8nA:
undetectable
4z90H-3d8nA:
undetectable
4z90J-3d8nA:
undetectable		 4z90F-3d8nA:
21.05
4z90G-3d8nA:
21.05
4z90H-3d8nA:
21.05
4z90J-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		6 / 9 LEU A 167
ALA A   4
LEU A 204
ALA A 210
LEU A 190
ALA A   6
 None
 1.22A 4z91F-3d8nA:
undetectable
4z91G-3d8nA:
undetectable
4z91H-3d8nA:
undetectable
4z91I-3d8nA:
undetectable
4z91J-3d8nA:
undetectable		 4z91F-3d8nA:
21.05
4z91G-3d8nA:
21.05
4z91H-3d8nA:
21.05
4z91I-3d8nA:
21.05
4z91J-3d8nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		4 / 7 THR A 234
ASP A 232
TYR A 230
GLY A 243
 None
 1.00A 5hwaA-3d8nA:
undetectable		 5hwaA-3d8nA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.60A 5qgjA-3d8nA:
undetectable		 5qgjA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.70A 5qglA-3d8nA:
undetectable		 5qglA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.62A 5qgmA-3d8nA:
undetectable		 5qgmA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.60A 5qgnA-3d8nA:
undetectable		 5qgnA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.65A 5qguA-3d8nA:
undetectable		 5qguA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.64A 5qgvA-3d8nA:
undetectable		 5qgvA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.64A 5qgwA-3d8nA:
undetectable		 5qgwA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.64A 5qgxA-3d8nA:
undetectable		 5qgxA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.66A 5qgyA-3d8nA:
undetectable		 5qgyA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.65A 5qgzA-3d8nA:
undetectable		 5qgzA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.67A 5qh0A-3d8nA:
undetectable		 5qh0A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.66A 5qh1A-3d8nA:
undetectable		 5qh1A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.66A 5qh2A-3d8nA:
undetectable		 5qh2A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.64A 5qh3A-3d8nA:
undetectable		 5qh3A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.64A 5qh4A-3d8nA:
undetectable		 5qh4A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.61A 5qh5A-3d8nA:
undetectable		 5qh5A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.61A 5qh6A-3d8nA:
undetectable		 5qh6A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.63A 5qh7A-3d8nA:
undetectable		 5qh7A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.61A 5qh9A-3d8nA:
undetectable		 5qh9A-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.66A 5qhaA-3d8nA:
undetectable		 5qhaA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.67A 5qhcA-3d8nA:
undetectable		 5qhcA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.66A 5qheA-3d8nA:
undetectable		 5qheA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.61A 5qhfA-3d8nA:
undetectable		 5qhfA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.63A 5qhgA-3d8nA:
undetectable		 5qhgA-3d8nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3d8n UROPORPHYRINOGEN-III
SYNTHASE
(Thermus
thermophilus) 		3 / 3 VAL A 125
VAL A  52
GLN A  50
 None
 0.62A 5qhhA-3d8nA:
undetectable		 5qhhA-3d8nA:
20.49