SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		4 / 8 SER A  73
ARG A  74
PHE A  77
GLY A  78
 NH4  A 304 (-2.6A)
None
NH4  A 304 ( 4.1A)
None
 1.08A 1fapB-3d9iA:
undetectable		 1fapB-3d9iA:
16.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		4 / 5 PRO A  20
ILE A  21
PRO A  61
TYR A  64
 SO4  A 150 (-4.7A)
None
None
SO4  A 150 (-4.6A)
 0.23A 3d9lA-3d9iA:
28.6
3d9lY-3d9iA:
undetectable		 3d9lA-3d9iA:
98.62
3d9lY-3d9iA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		4 / 7 SER A  89
GLU A 126
ILE A 127
ASN A  90
 GOL  A1002 (-3.1A)
None
GOL  A1002 (-4.8A)
SO4  A 147 ( 3.4A)
 1.12A 4d33B-3d9iA:
undetectable		 4d33B-3d9iA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		4 / 8 SER A  89
GLU A 126
ILE A 127
ASN A  90
 GOL  A1002 (-3.1A)
None
GOL  A1002 (-4.8A)
SO4  A 147 ( 3.4A)
 1.12A 4d39A-3d9iA:
undetectable		 4d39A-3d9iA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		4 / 7 SER A  89
GLU A 126
ILE A 127
ASN A  90
 GOL  A1002 (-3.1A)
None
GOL  A1002 (-4.8A)
SO4  A 147 ( 3.4A)
 1.01A 4d39B-3d9iA:
undetectable		 4d39B-3d9iA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		3 / 3 LEU A  11
THR A  95
ASN A  98
 None
 0.72A 6baaE-3d9iA:
undetectable		 6baaE-3d9iA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		3 / 3 LEU A  11
THR A  95
ASN A  98
 None
 0.72A 6baaF-3d9iA:
undetectable		 6baaF-3d9iA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		3 / 3 LEU A  11
THR A  95
ASN A  98
 None
 0.73A 6baaG-3d9iA:
undetectable		 6baaG-3d9iA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3d9i RNA-BINDING PROTEIN
16
(Homo
sapiens) 		3 / 3 LEU A  11
THR A  95
ASN A  98
 None
 0.73A 6baaH-3d9iA:
undetectable		 6baaH-3d9iA:
6.45