SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 10 LEU A 224
ILE A 269
LEU A 276
LEU A 279
VAL A  57
None
1.20A 1cqpA-3d9wA:
undetectable
1cqpB-3d9wA:
undetectable
1cqpA-3d9wA:
19.03
1cqpB-3d9wA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 7 GLU A  52
LEU A  54
ASP A 275
LEU A 276
GLY A 273
None
1.27A 1mt1H-3d9wA:
undetectable
1mt1K-3d9wA:
undetectable
1mt1H-3d9wA:
15.86
1mt1K-3d9wA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 11 LEU A 122
GLY A  87
LEU A  69
LEU A  93
HIS A  45
None
1.05A 1mx1A-3d9wA:
undetectable
1mx1A-3d9wA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 5 GLU A  52
LEU A  54
ASP A 275
LEU A 276
None
1.25A 1n13B-3d9wA:
undetectable
1n13C-3d9wA:
undetectable
1n13B-3d9wA:
15.86
1n13C-3d9wA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 7 GLU A  52
LEU A  54
ASP A 275
LEU A 276
GLY A 273
None
1.27A 1n13D-3d9wA:
0.0
1n13E-3d9wA:
undetectable
1n13D-3d9wA:
15.86
1n13E-3d9wA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 8 LEU A  54
ASP A 275
LEU A 276
GLY A 273
GLU A  52
None
1.28A 1n13A-3d9wA:
undetectable
1n13F-3d9wA:
undetectable
1n13A-3d9wA:
10.03
1n13F-3d9wA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 6 GLU A  52
LEU A  54
ASP A 275
LEU A 276
GLY A 273
None
1.30A 1n13H-3d9wA:
undetectable
1n13K-3d9wA:
undetectable
1n13H-3d9wA:
15.86
1n13K-3d9wA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 7 LEU A  54
ASP A 275
LEU A 276
GLY A 273
GLU A  52
None
1.31A 1n13G-3d9wA:
undetectable
1n13J-3d9wA:
undetectable
1n13G-3d9wA:
10.03
1n13J-3d9wA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 8 GLU A  52
LEU A  54
ASP A 275
LEU A 276
GLY A 273
None
1.32A 2qqdB-3d9wA:
undetectable
2qqdC-3d9wA:
undetectable
2qqdB-3d9wA:
15.52
2qqdC-3d9wA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 9 ARG A  95
ALA A  20
GLU A  94
GLY A  87
LEU A  88
None
1.21A 2v0mB-3d9wA:
undetectable
2v0mB-3d9wA:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
6 / 6 PHE A  51
TYR A  81
CYH A  82
VAL A 107
THR A 118
PHE A 218
None
0.66A 3ltwA-3d9wA:
34.8
3ltwA-3d9wA:
35.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 8 ALA A 117
GLY A 105
THR A 104
THR A 194
None
0.95A 3rglA-3d9wA:
undetectable
3rglA-3d9wA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 6 GLY A 186
TRP A 187
GLU A 155
ARG A 164
None
1.45A 4bqfA-3d9wA:
undetectable
4bqfA-3d9wA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
3 / 3 PHE A  27
ASP A  19
ARG A  31
None
0.86A 4eahF-3d9wA:
undetectable
4eahF-3d9wA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
3 / 3 PHE A  27
ASP A  19
ARG A  31
None
0.85A 4eahG-3d9wA:
undetectable
4eahG-3d9wA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 11 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.25A 4ygfA-3d9wA:
undetectable
4ygfA-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 11 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.25A 4ygfC-3d9wA:
undetectable
4ygfC-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 11 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.28A 4ygfD-3d9wA:
undetectable
4ygfD-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 12 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.24A 4ygfG-3d9wA:
undetectable
4ygfG-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 10 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.23A 4yhaB-3d9wA:
undetectable
4yhaB-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 12 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.24A 4yhaG-3d9wA:
undetectable
4yhaG-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 7 VAL A 137
LEU A  16
TYR A  21
ALA A  90
None
0.87A 5f1aB-3d9wA:
undetectable
5f1aB-3d9wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 6 PRO A 245
GLY A 159
PHE A 227
ARG A 141
None
1.33A 5jcnB-3d9wA:
undetectable
5jcnB-3d9wA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 10 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.22A 5tt3A-3d9wA:
undetectable
5tt3A-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 9 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.16A 5tt3B-3d9wA:
undetectable
5tt3B-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 10 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.25A 5tt3C-3d9wA:
undetectable
5tt3C-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 9 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.25A 5tt3E-3d9wA:
undetectable
5tt3E-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 9 HIS A  45
VAL A  42
VAL A 137
LEU A  93
ALA A  92
None
1.26A 5tt3G-3d9wA:
undetectable
5tt3G-3d9wA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
4 / 5 GLY A 159
ASP A 160
GLN A 181
MET A 109
None
1.23A 5zrfB-3d9wA:
undetectable
5zrfB-3d9wA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 12 LEU A  38
GLY A  99
PHE A 203
PHE A  89
VAL A 137
None
1.22A 6a94A-3d9wA:
undetectable
6a94A-3d9wA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 12 LEU A  41
VAL A 124
LEU A 122
ALA A  92
LEU A  93
None
1.07A 6ajiA-3d9wA:
undetectable
6ajiA-3d9wA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)
3d9w PUTATIVE
ACETYLTRANSFERASE

(Nocardia
farcinica)
5 / 12 VAL A 100
LEU A  22
LEU A  96
LEU A  18
LEU A  66
None
0.99A 6b0cD-3d9wA:
undetectable
6b0cD-3d9wA:
14.33