SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 110
ILE A  88
PHE A  36
LEU A  38
ILE A  21
 None
 1.04A 1xozA-3d9yA:
undetectable		 1xozA-3d9yA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		5 / 12 ILE A  87
GLY A  80
TYR A  79
LEU A  46
ILE A  78
 None
 1.11A 2y7kD-3d9yA:
undetectable		 2y7kD-3d9yA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 121
ILE A  61
LEU A  63
TYR A   5
ILE A  43
 None
 1.15A 3zosB-3d9yA:
undetectable		 3zosB-3d9yA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A  91
ASP A  52
THR A  59
SER A  77
GLU A  74
 None
 1.31A 5hfjG-3d9yA:
undetectable		 5hfjG-3d9yA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A  10
ILE A  21
ILE A  87
GLU A  85
GLU A 115
 None
 1.49A 5igzA-3d9yA:
undetectable		 5igzA-3d9yA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		4 / 4 GLU A  42
PRO A  40
ILE A  43
LEU A  38
 None
 1.27A 5m45A-3d9yA:
6.0		 5m45A-3d9yA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3d9y PROFILIN
(Schizosaccharomy
ces
pombe) 		4 / 4 GLU A  42
PRO A  40
ILE A  43
LEU A  38
 None
 1.28A 5m45J-3d9yA:
undetectable		 5m45J-3d9yA:
10.21