SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3da1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 GLY A  32
THR A 173
ALA A 227
GLY A  25
ILE A 369
 None
None
None
FAD  A 609 ( 4.0A)
None
 0.88A 1bx4A-3da1A:
3.4		 1bx4A-3da1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 6 VAL A 186
GLY A  45
LEU A  19
GLU A  16
 None
 0.88A 1fduD-3da1A:
3.4		 1fduD-3da1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 4 GLY A  41
ASP A  20
GLY A 391
THR A 384
 None
 0.89A 1hxbB-3da1A:
undetectable		 1hxbB-3da1A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 PHE A 361
ALA A 387
ILE A 369
ILE A  33
 None
 0.94A 1oniD-3da1A:
undetectable
1oniF-3da1A:
undetectable		 1oniD-3da1A:
14.57
1oniF-3da1A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 PHE A  52
ILE A  33
GLY A  30
GLY A  27
ILE A  24
 None
None
None
FAD  A 609 (-3.4A)
FAD  A 609 (-4.6A)
 1.04A 1sg9B-3da1A:
undetectable		 1sg9B-3da1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 10 LEU A  46
PHE A   2
ALA A  34
ILE A 176
LEU A  35
 None
 1.13A 1yi4A-3da1A:
undetectable		 1yi4A-3da1A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 11 VAL A 232
ASN A 226
ILE A 369
ILE A 343
LEU A 247
 None
 1.07A 1z11A-3da1A:
undetectable		 1z11A-3da1A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 11 VAL A 232
ASN A 226
ILE A 369
ILE A 343
LEU A 247
 None
 1.04A 1z11B-3da1A:
undetectable		 1z11B-3da1A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 10 VAL A 232
ASN A 226
ILE A 369
ILE A 343
LEU A 247
 None
 1.09A 1z11D-3da1A:
undetectable		 1z11D-3da1A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 10 LYS A 242
SER A 241
PHE A 360
ALA A 370
LEU A 366
 None
 1.06A 2bxqA-3da1A:
undetectable		 2bxqA-3da1A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 ILE A  24
GLY A  25
GLY A  27
ILE A 369
ALA A 228
 FAD  A 609 (-4.6A)
FAD  A 609 ( 4.0A)
FAD  A 609 (-3.4A)
None
FAD  A 609 ( 3.9A)
 0.96A 2fk8A-3da1A:
undetectable		 2fk8A-3da1A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 GLY A  25
GLY A  26
VAL A 193
LEU A 235
 FAD  A 609 ( 4.0A)
None
FAD  A 609 ( 3.8A)
FAD  A 609 (-4.2A)
 0.63A 2oa1B-3da1A:
9.2		 2oa1B-3da1A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 9 ILE A  42
ALA A 381
VAL A 385
GLU A 382
 None
 0.80A 2vufA-3da1A:
undetectable		 2vufA-3da1A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 GLU A 482
ARG A 171
GLU A 175
SER A 406
 None
 0.54A 2zt7A-3da1A:
1.5		 2zt7A-3da1A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		3 / 3 LEU A 325
VAL A 332
ARG A 261
 None
 0.89A 3b0wB-3da1A:
undetectable		 3b0wB-3da1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 VAL A 225
VAL A 193
VAL A 385
ILE A  42
THR A 384
 None
FAD  A 609 ( 3.8A)
None
None
None
 1.25A 3dl9A-3da1A:
undetectable		 3dl9A-3da1A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 ILE A 176
GLY A  32
GLY A  30
ALA A 227
ALA A  37
 None
 1.11A 3jayA-3da1A:
undetectable		 3jayA-3da1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 8 THR A 400
GLY A  32
ALA A  34
THR A  44
ILE A  42
 None
 1.21A 3jusB-3da1A:
undetectable		 3jusB-3da1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 9 THR A 400
GLY A  32
ALA A  34
THR A  44
ILE A  42
 None
 1.21A 3jusB-3da1A:
undetectable		 3jusB-3da1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		3 / 3 ARG A 311
THR A  61
THR A 295
 None
FAD  A 609 (-3.3A)
None
 0.60A 3k2hB-3da1A:
undetectable		 3k2hB-3da1A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 4 GLY A  41
ASP A  20
GLY A 391
THR A 384
 None
 0.91A 3k4vC-3da1A:
undetectable		 3k4vC-3da1A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 SER A  57
ILE A  33
ASP A  36
LEU A  35
LEU A 174
 FAD  A 609 (-2.9A)
None
None
None
None
 1.31A 3lcvB-3da1A:
undetectable		 3lcvB-3da1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		3 / 3 TYR A 313
ASP A 271
ASP A 275
 None
 0.75A 3r24A-3da1A:
undetectable		 3r24A-3da1A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 7 LEU A 366
ASN A 226
ALA A 228
GLY A  30
ILE A  33
 None
None
FAD  A 609 ( 3.9A)
None
None
 1.44A 3spkB-3da1A:
undetectable		 3spkB-3da1A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 LEU A  46
LEU A  22
LEU A  21
ILE A 369
LEU A 235
 None
None
None
None
FAD  A 609 (-4.2A)
 1.29A 4j24C-3da1A:
undetectable		 4j24C-3da1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 6 GLU A 482
ARG A 171
GLU A 175
SER A 406
 None
 0.96A 4kr3A-3da1A:
undetectable		 4kr3A-3da1A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 8 SER A  58
ARG A 493
VAL A 253
GLY A 252
 None
None
None
FAD  A 609 (-3.5A)
 0.82A 4mk4A-3da1A:
undetectable		 4mk4A-3da1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		3 / 3 ALA A 381
GLN A  38
GLY A 184
 None
 0.65A 4odoC-3da1A:
undetectable		 4odoC-3da1A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 PHE A 270
ALA A 318
LEU A 264
PHE A 262
 None
 1.09A 4uymA-3da1A:
undetectable		 4uymA-3da1A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 6 HIS A  65
GLY A  66
GLU A 164
ARG A  86
 FAD  A 609 (-4.0A)
None
None
None
 1.19A 4zbqA-3da1A:
undetectable		 4zbqA-3da1A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.75A 5bs8A-3da1A:
undetectable
5bs8C-3da1A:
undetectable
5bs8D-3da1A:
undetectable		 5bs8A-3da1A:
23.91
5bs8C-3da1A:
23.91
5bs8D-3da1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.74A 5bs8A-3da1A:
undetectable
5bs8B-3da1A:
undetectable
5bs8C-3da1A:
undetectable		 5bs8A-3da1A:
23.91
5bs8B-3da1A:
19.35
5bs8C-3da1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.74A 5btdA-3da1A:
undetectable
5btdB-3da1A:
undetectable
5btdC-3da1A:
undetectable		 5btdA-3da1A:
23.91
5btdB-3da1A:
19.35
5btdC-3da1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.77A 5btdA-3da1A:
undetectable
5btdC-3da1A:
undetectable
5btdD-3da1A:
undetectable		 5btdA-3da1A:
23.91
5btdC-3da1A:
23.91
5btdD-3da1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 6 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.74A 5btgA-3da1A:
undetectable
5btgB-3da1A:
undetectable
5btgC-3da1A:
undetectable		 5btgA-3da1A:
23.91
5btgB-3da1A:
19.35
5btgC-3da1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 7 ALA A 227
ARG A 378
GLY A 376
GLU A  85
 None
 0.84A 5btgA-3da1A:
undetectable
5btgC-3da1A:
undetectable
5btgD-3da1A:
undetectable		 5btgA-3da1A:
23.91
5btgC-3da1A:
23.91
5btgD-3da1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 GLY A  32
THR A 173
ALA A 227
GLY A  25
ILE A 369
 None
None
None
FAD  A 609 ( 4.0A)
None
 0.84A 5kb6A-3da1A:
3.4		 5kb6A-3da1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 PRO A 105
LEU A 151
VAL A 268
ILE A 282
PHE A 262
 None
 1.26A 5tiwB-3da1A:
undetectable		 5tiwB-3da1A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 GLY A  12
GLY A 205
PHE A 196
VAL A 193
ILE A  24
 None
None
None
FAD  A 609 ( 3.8A)
FAD  A 609 (-4.6A)
 0.88A 5tuiB-3da1A:
13.7		 5tuiB-3da1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 11 ILE A  28
GLY A  27
GLY A  26
LEU A 405
LEU A  35
 FAD  A 609 (-4.3A)
FAD  A 609 (-3.4A)
None
None
None
 0.86A 5twjD-3da1A:
undetectable		 5twjD-3da1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		4 / 9 ILE A 343
ILE A 359
ILE A 367
LEU A 366
 None
 0.79A 5vkqB-3da1A:
undetectable
5vkqC-3da1A:
undetectable		 5vkqB-3da1A:
15.55
5vkqC-3da1A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 TYR A 444
LEU A 443
PHE A 491
VAL A 512
LEU A 452
 None
 1.40A 6djzB-3da1A:
undetectable		 6djzB-3da1A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Bacillus
halodurans) 		5 / 12 ILE A 367
GLY A 391
ALA A 389
ILE A  33
LEU A  21
 None
 1.10A 6dwnD-3da1A:
undetectable		 6dwnD-3da1A:
8.82