SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 274
LEU A 259
MET A 306
 None
 0.80A 1ya3B-3dadA:
undetectable		 1ya3B-3dadA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 11 VAL A 278
THR A 279
ALA A 333
ASP A 338
PHE A 294
 None
 1.21A 2admB-3dadA:
undetectable		 2admB-3dadA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 GLN A  91
LEU A  82
LEU A  51
SER A  44
LEU A  45
 None
 1.41A 2ceoB-3dadA:
undetectable		 2ceoB-3dadA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 PHE A 146
LEU A 124
LEU A 139
ALA A 183
 None
 0.90A 2vcvK-3dadA:
2.1		 2vcvK-3dadA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 PRO A  65
LEU A  66
ARG A 113
 None
 0.92A 3aqiA-3dadA:
undetectable		 3aqiA-3dadA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A 280
TYR A 276
LEU A 273
LEU A 227
 None
 0.93A 3f33A-3dadA:
undetectable		 3f33A-3dadA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 129
ASP A  27
ASP A  25
ALA A 122
 None
 1.24A 3uj6A-3dadA:
undetectable		 3uj6A-3dadA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 309
GLN A 304
ASN A 258
ALA A 300
ILE A 281
 None
 1.04A 3ut5D-3dadA:
undetectable		 3ut5D-3dadA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 HIS A 158
SER A 159
SER A 117
VAL A 120
 None
 1.35A 4a99D-3dadA:
undetectable		 4a99D-3dadA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 VAL A  16
THR A 109
PRO A 108
TYR A  99
ILE A  55
 None
 1.37A 4eb6B-3dadA:
undetectable
4eb6C-3dadA:
undetectable		 4eb6B-3dadA:
22.98
4eb6C-3dadA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A  45
LYS A  14
LEU A  88
GLU A  89
 None
 1.20A 4f3tA-3dadA:
undetectable		 4f3tA-3dadA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 8 GLY A 193
GLY A 185
LEU A 225
VAL A 228
TYR A 232
 None
 1.26A 4fgzA-3dadA:
undetectable		 4fgzA-3dadA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 GLY A 193
LEU A 225
VAL A 228
TYR A 232
 None
 0.70A 4fgzB-3dadA:
undetectable		 4fgzB-3dadA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 GLN A  91
LEU A  82
LEU A  51
SER A  44
LEU A  45
 None
 1.19A 4yiaA-3dadA:
undetectable		 4yiaA-3dadA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3dad FH1/FH2
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A 221
THR A 203
LEU A 187
 None
 0.66A 5m66D-3dadA:
undetectable		 5m66D-3dadA:
22.47