SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dal'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.06A 1p6kA-3dalA:
undetectable		 1p6kA-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.01A 1p6kB-3dalA:
undetectable		 1p6kB-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.06A 1rs6A-3dalA:
undetectable		 1rs6A-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.02A 1rs6B-3dalA:
undetectable		 1rs6B-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 0.95A 1rs7B-3dalA:
undetectable		 1rs7B-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 6 TRP A  99
ASN A 120
LEU A  79
PHE A 147
 None
 1.49A 1rukH-3dalA:
undetectable
1rukL-3dalA:
undetectable		 1rukH-3dalA:
17.33
1rukL-3dalA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.05A 1zzqA-3dalA:
undetectable		 1zzqA-3dalA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 0.97A 1zzqB-3dalA:
undetectable		 1zzqB-3dalA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.31A 1zzuA-3dalA:
undetectable		 1zzuA-3dalA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.02A 1zzuB-3dalA:
undetectable		 1zzuB-3dalA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 7 TYR A 163
GLU A  14
TYR A 102
TRP A  99
 None
 1.48A 3cotA-3dalA:
undetectable		 3cotA-3dalA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.08A 3n62A-3dalA:
undetectable		 3n62A-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.10A 3n62B-3dalA:
undetectable		 3n62B-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.11A 3n66B-3dalA:
undetectable		 3n66B-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.24A 5vunA-3dalA:
undetectable		 5vunA-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.14A 5vunB-3dalA:
undetectable		 5vunB-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.13A 5vuoB-3dalA:
undetectable		 5vuoB-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dal PR DOMAIN ZINC
FINGER PROTEIN 1
(Homo
sapiens) 		4 / 8 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.15A 6auuB-3dalA:
undetectable		 6auuB-3dalA:
19.37