SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  69
PRO A  82
THR A  80
 None
 0.96A 1dscC-3daoA:
undetectable		 1dscC-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  80
THR A  69
PRO A  82
 None
 0.87A 1fjaC-3daoA:
undetectable		 1fjaC-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  80
THR A  69
PRO A  82
 None
 0.87A 1fjaD-3daoA:
undetectable		 1fjaD-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		5 / 12 CYH A 162
ASP A 103
TRP A 183
ILE A 121
PRO A 120
 None
None
1PE  A 265 ( 4.0A)
None
None
 1.44A 1g60B-3daoA:
4.2		 1g60B-3daoA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  69
PRO A  82
THR A  80
 None
 0.88A 1i3wE-3daoA:
undetectable		 1i3wE-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  80
THR A  69
PRO A  82
 None
 0.86A 1i3wE-3daoA:
undetectable		 1i3wE-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  80
THR A  69
PRO A  82
 None
 0.85A 1i3wF-3daoA:
undetectable		 1i3wF-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  80
THR A  69
PRO A  82
 None
 0.78A 1mnvD-3daoA:
undetectable		 1mnvD-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  69
PRO A  82
THR A  80
 None
 0.87A 1ovfB-3daoA:
undetectable		 1ovfB-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 5 ARG A  45
PHE A  39
PHE A  54
LEU A  53
 None
 1.24A 2y69C-3daoA:
undetectable
2y69J-3daoA:
undetectable		 2y69C-3daoA:
19.58
2y69J-3daoA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 5 ARG A  45
PHE A  39
PHE A  54
LEU A  53
 None
 1.24A 3abmC-3daoA:
undetectable
3abmJ-3daoA:
undetectable		 3abmC-3daoA:
19.58
3abmJ-3daoA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 6 THR A 151
VAL A 152
GLU A 159
CYH A 162
 1PE  A 265 ( 4.1A)
None
None
None
 0.98A 3b6rB-3daoA:
undetectable		 3b6rB-3daoA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 7 TRP A  88
PHE A 166
VAL A  95
ILE A 147
 None
 0.87A 3zjqA-3daoA:
undetectable		 3zjqA-3daoA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 7 TRP A  88
PHE A 166
VAL A  95
ILE A 147
 None
 0.89A 3zjqB-3daoA:
undetectable		 3zjqB-3daoA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 THR A  69
PRO A  82
THR A  80
 None
 0.86A 4hivD-3daoA:
undetectable		 4hivD-3daoA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		5 / 12 ASP A 146
PHE A 111
ILE A 147
ALA A 106
PHE A 113
 None
 1.33A 4wh5A-3daoA:
undetectable		 4wh5A-3daoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		5 / 8 ILE A  77
VAL A  71
PRO A 109
ALA A 196
THR A 195
 None
 1.44A 6cduD-3daoA:
undetectable
6cduE-3daoA:
undetectable		 6cduD-3daoA:
20.47
6cduE-3daoA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 LEU A  62
LEU A  78
ARG A 203
 None
 0.58A 6fgcA-3daoA:
undetectable		 6fgcA-3daoA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		3 / 3 LEU A  62
LEU A  78
ARG A 203
 None
 0.65A 6fgdA-3daoA:
2.4		 6fgdA-3daoA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3dao PUTATIVE PHOSPHATE
([Eubacterium]
rectale) 		4 / 4 ASP A 205
ILE A 201
PRO A 208
LEU A 206
 None
 1.43A 6mkeB-3daoA:
undetectable		 6mkeB-3daoA:
16.18