SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3das'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		3 / 3 ASP A 168
ASP A 162
LYS A 175
 None
 1.03A 1lqtB-3dasA:
undetectable		 1lqtB-3dasA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		3 / 3 ASP A 168
ASP A 162
LYS A 175
 None
 1.04A 1lquB-3dasA:
undetectable		 1lquB-3dasA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 6 ARG A 311
GLN A 205
ASN A 203
LEU A 215
 PQQ  A4331 (-2.9A)
PQQ  A4331 (-3.0A)
PQQ  A4331 (-3.9A)
None
 1.26A 2nyrA-3dasA:
undetectable		 2nyrA-3dasA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 10 ASP A 329
ARG A 311
ILE A 268
ILE A 288
GLY A 282
 PQQ  A4331 ( 4.9A)
PQQ  A4331 (-2.9A)
None
None
ARA  A 349 (-4.1A)
 1.30A 2v0mA-3dasA:
undetectable		 2v0mA-3dasA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 269
PRO A 315
VAL A 313
GLN A 300
PHE A 302
 None
None
None
EDO  A4334 (-4.3A)
EDO  A4334 ( 4.2A)
 1.21A 2v95A-3dasA:
undetectable		 2v95A-3dasA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 206
PRO A 265
GLY A 156
ALA A 208
ILE A 176
 None
 0.95A 3ku1A-3dasA:
undetectable		 3ku1A-3dasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 206
PRO A 265
GLY A 156
ALA A 208
ILE A 176
 None
 0.95A 3ku1C-3dasA:
undetectable		 3ku1C-3dasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 206
PRO A 265
GLY A 156
ALA A 208
ILE A 176
 None
 0.97A 3ku1H-3dasA:
undetectable		 3ku1H-3dasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		3 / 3 ARG A 178
TRP A 209
GLY A 148
 None
 0.79A 4e7cA-3dasA:
undetectable		 4e7cA-3dasA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 9 ALA A 217
GLY A 206
GLY A 156
HIS A 201
ILE A 176
 None
 1.05A 4eatB-3dasA:
undetectable		 4eatB-3dasA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 6 PRO A 254
GLY A 221
ALA A 242
GLN A 205
 None
CA  A 351 ( 4.6A)
None
PQQ  A4331 (-3.0A)
 1.07A 4g0uA-3dasA:
undetectable		 4g0uA-3dasA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 11 VAL A  71
ALA A  53
SER A 103
SER A  75
GLY A  81
 None
 1.26A 4mmaA-3dasA:
undetectable		 4mmaA-3dasA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 7 THR A 157
GLY A 143
ALA A 155
ILE A 109
 None
 0.95A 4txnA-3dasA:
undetectable		 4txnA-3dasA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 7 THR A 157
GLY A 143
ALA A 155
ILE A 109
 None
 0.94A 4txnB-3dasA:
undetectable		 4txnB-3dasA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 7 THR A 157
GLY A 143
ALA A 155
ILE A 109
 None
 0.91A 4txnC-3dasA:
undetectable		 4txnC-3dasA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 7 THR A 157
GLY A 143
ALA A 155
ILE A 109
 None
 0.96A 4txnD-3dasA:
undetectable		 4txnD-3dasA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLU A 159
GLY A 221
ASN A 203
ALA A 217
ASN A 229
 None
CA  A 351 ( 4.6A)
PQQ  A4331 (-3.9A)
None
CA  A 350 ( 4.4A)
 1.00A 5kc4A-3dasA:
undetectable		 5kc4A-3dasA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 10 ARG A 311
ILE A 176
GLY A 156
GLY A 143
ALA A 217
 PQQ  A4331 (-2.9A)
None
None
None
None
 1.01A 5o96C-3dasA:
undetectable
5o96D-3dasA:
undetectable		 5o96C-3dasA:
23.88
5o96D-3dasA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_C_SAMC1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A  81
SER A 266
ASN A 141
HIS A 140
PHE A 220
 None
None
None
PQQ  A4331 (-3.9A)
PQQ  A4331 (-3.5A)
 1.16A 5ttfC-3dasA:
undetectable		 5ttfC-3dasA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 144
ASP A  51
GLY A  81
LEU A  83
ASN A 203
 None
None
None
None
PQQ  A4331 (-3.9A)
 1.20A 5x7pB-3dasA:
0.0		 5x7pB-3dasA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		4 / 5 THR A 312
ARG A 144
THR A 328
ASP A 333
 None
 1.44A 6ectA-3dasA:
undetectable		 6ectA-3dasA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3das PUTATIVE
OXIDOREDUCTASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 158
GLY A 174
ASP A 162
PRO A 240
GLY A 200
 None
 1.14A 6gneB-3dasA:
undetectable		 6gneB-3dasA:
23.62