SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3daw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3daw TWINFILIN-1
(Mus
musculus) 		4 / 7 ILE B 212
TYR B 236
PHE B 238
PHE B 255
 None
 1.04A 1e71M-3dawB:
undetectable		 1e71M-3dawB:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3daw TWINFILIN-1
(Mus
musculus) 		4 / 7 ILE B 212
TYR B 236
PHE B 238
PHE B 255
 None
 1.05A 1e72M-3dawB:
undetectable		 1e72M-3dawB:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 3daw TWINFILIN-1
(Mus
musculus) 		4 / 6 GLN B 188
LEU B 190
GLU B 191
LEU B 287
 None
 0.87A 3h5gA-3dawB:
undetectable
3h5gC-3dawB:
undetectable		 3h5gA-3dawB:
12.74
3h5gC-3dawB:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3daw TWINFILIN-1
(Mus
musculus) 		4 / 6 LEU B 287
GLN B 188
LEU B 190
GLU B 191
 None
 0.65A 3h5gB-3dawB:
undetectable
3h5gC-3dawB:
undetectable		 3h5gB-3dawB:
12.74
3h5gC-3dawB:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 3daw TWINFILIN-1
(Mus
musculus) 		5 / 9 HIS B 243
SER B 244
ASP B 310
TYR B 241
LEU B 222
 None
 1.32A 4bvvA-3dawB:
undetectable		 4bvvA-3dawB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3daw TWINFILIN-1
(Mus
musculus) 		4 / 5 LEU B 279
GLU B 284
LEU B 193
HIS B 237
 None
 1.37A 4xi3B-3dawB:
undetectable		 4xi3B-3dawB:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3daw TWINFILIN-1
(Mus
musculus) 		5 / 7 ILE B 282
LEU B 279
VAL B 201
LEU B 190
LEU B 287
 None
 1.50A 6g9bA-3dawB:
undetectable
6g9bB-3dawB:
undetectable		 6g9bA-3dawB:
18.40
6g9bB-3dawB:
15.85