SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3db1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERR_A_RALA600_2 (ESTROGEN RECEPTOR)	3db1	STS-2 PROTEIN (Mus musculus)	4 / 6	LEU A 547 LEU A 583 LEU A 495 LEU A 492	None	0.86A	1errA-3db1A: undetectable	1errA-3db1A: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VRM_A_VD3A502_1 (VITAMIN D(3) 25-HYDROXYLASE)	3db1	STS-2 PROTEIN (Mus musculus)	5 / 12	ILE A 364 LEU A 583 ALA A 424 ILE A 545 LEU A 460	None	1.00A	3vrmA-3db1A: undetectable	3vrmA-3db1A: 23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA506_0 (FERROCHELATASE, MITOCHONDRIAL)	3db1	STS-2 PROTEIN (Mus musculus)	4 / 4	PRO A 561 LEU A 562 ILE A 361 ARG A 359	None	1.33A	4f4dA-3db1A: undetectable	4f4dA-3db1A: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	3db1	STS-2 PROTEIN (Mus musculus)	4 / 7	GLY A 544 ASP A 542 GLY A 360 GLU A 590	None	0.91A	4z53A-3db1A: undetectable 4z53B-3db1A: undetectable	4z53A-3db1A: 15.66 4z53B-3db1A: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_1 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	3db1	STS-2 PROTEIN (Mus musculus)	3 / 3	ARG A 425 LYS A 454 GLU A 458	None	0.66A	5d0yA-3db1A: undetectable	5d0yA-3db1A: 19.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ERR_A_RALA600_2","ESTROGEN RECEPTOR","3db1","STS-2 PROTEIN","Mus musculus",4,"LEU A 547;LEU A 583;LEU A 495;LEU A 492","None","0.86A","1errA-3db1A:undetectable","1errA-3db1A:20.75"],["3VRM_A_VD3A502_1","VITAMIN D(3) 25-HYDROXYLASE","3db1","STS-2 PROTEIN","Mus musculus",5,"ILE A 364;LEU A 583;ALA A 424;ILE A 545;LEU A 460","None","1.00A","3vrmA-3db1A:undetectable","3vrmA-3db1A:23.65"],["4F4D_A_CHDA506_0","FERROCHELATASE, MITOCHONDRIAL","3db1","STS-2 PROTEIN","Mus musculus",4,"PRO A 561;LEU A 562;ILE A 361;ARG A 359","None","1.33A","4f4dA-3db1A:undetectable","4f4dA-3db1A:21.33"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","3db1","STS-2 PROTEIN","Mus musculus",4,"GLY A 544;ASP A 542;GLY A 360;GLU A 590","None","0.91A","4z53A-3db1A:undetectable;4z53B-3db1A:undetectable","4z53A-3db1A:15.66;4z53B-3db1A:15.66"],["5D0Y_A_FOLA201_1","CONSERVED HYPOTHETICAL MEMBRANE PROTEIN","3db1","STS-2 PROTEIN","Mus musculus",3,"ARG A 425;LYS A 454;GLU A 458","None","0.66A","5d0yA-3db1A:undetectable","5d0yA-3db1A:19.93"]]