SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3db2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 5 ARG A  63
ALA A   8
ASP A  65
GLY A   6
 None
 1.05A 1e7bA-3db2A:
undetectable		 1e7bA-3db2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 5 ARG A  63
ALA A   8
ASP A  65
GLY A   6
 None
 0.98A 1e7cA-3db2A:
2.2		 1e7cA-3db2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 6 ILE A 186
VAL A 183
VAL A  73
ILE A  82
ILE A  10
 None
 1.41A 1uwhB-3db2A:
undetectable		 1uwhB-3db2A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 5 PHE A 240
LEU A 131
PHE A 257
SER A 263
 None
 1.22A 1wrlC-3db2A:
undetectable		 1wrlC-3db2A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 7 ALA A 323
SER A 326
ASP A 109
ILE A  92
 None
 0.95A 1yc5A-3db2A:
3.1		 1yc5A-3db2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 TRP A  15
ALA A  22
VAL A  18
 None
 0.73A 2izqA-3db2A:
undetectable
2izqB-3db2A:
undetectable		 2izqA-3db2A:
6.75
2izqB-3db2A:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 5 LEU A 178
GLN A 217
THR A 232
HIS A 341
 None
 1.19A 2zj0B-3db2A:
2.6		 2zj0B-3db2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 5 LEU A 178
GLN A 217
THR A 232
HIS A 341
 None
 1.28A 2zj0C-3db2A:
7.7		 2zj0C-3db2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 ILE A  10
VAL A  81
ILE A  82
ILE A  92
VAL A  94
 None
 1.08A 3kpdC-3db2A:
undetectable		 3kpdC-3db2A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 ALA A  22
VAL A  18
TRP A  15
 None
 0.71A 3l8lA-3db2A:
undetectable
3l8lB-3db2A:
undetectable		 3l8lA-3db2A:
6.75
3l8lB-3db2A:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 ALA A  22
VAL A  18
TRP A  15
 None
 0.63A 3l8lC-3db2A:
undetectable
3l8lD-3db2A:
undetectable		 3l8lC-3db2A:
6.75
3l8lD-3db2A:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 TYR A  35
ILE A  10
GLU A  80
GLU A  58
VAL A  81
 None
 1.39A 3qwuA-3db2A:
undetectable		 3qwuA-3db2A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A 220
ALA A 151
ILE A 149
ALA A 228
ILE A 242
 None
 0.94A 4o2bD-3db2A:
4.5		 4o2bD-3db2A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 ASP A 256
LEU A 255
PHE A 257
 None
 0.69A 4pthA-3db2A:
2.1		 4pthA-3db2A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 ARG A 290
ASP A 291
ARG A 275
 None
 0.66A 4wq4B-3db2A:
undetectable		 4wq4B-3db2A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 LEU A 302
VAL A 299
ASP A 267
 None
 0.68A 4y8wC-3db2A:
undetectable		 4y8wC-3db2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 ALA A 249
ASN A 250
LEU A 251
 None
 0.45A 5i1pD-3db2A:
undetectable		 5i1pD-3db2A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 9 ILE A 186
VAL A 199
THR A 218
ASN A 216
 None
 1.04A 5lg3I-3db2A:
undetectable		 5lg3I-3db2A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 VAL A 340
ILE A 348
LEU A 220
VAL A 196
ILE A 186
 None
 0.92A 5mueA-3db2A:
undetectable		 5mueA-3db2A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		3 / 3 GLY A 175
THR A 214
ASN A 212
 None
 0.66A 5odiG-3db2A:
undetectable		 5odiG-3db2A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 ILE A  98
LEU A 334
ASP A 109
ASP A 103
ILE A  82
 None
 1.44A 6dwnB-3db2A:
undetectable		 6dwnB-3db2A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 GLY A 246
GLY A 144
PHE A 277
GLU A 276
LEU A 251
 None
 1.03A 6ectA-3db2A:
3.7		 6ectA-3db2A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 12 GLY A 246
GLY A 144
PHE A 277
GLU A 276
LEU A 251
 None
 0.99A 6ecxA-3db2A:
undetectable		 6ecxA-3db2A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		4 / 7 ILE A 186
GLN A 190
GLU A 223
VAL A 332
 None
 1.06A 6j20A-3db2A:
undetectable		 6j20A-3db2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE
(Desulfitobacteri
um
hafniense) 		5 / 9 ILE A  98
ALA A 323
GLY A 322
LEU A 120
GLY A 116
 None
 1.22A 6nm4B-3db2A:
undetectable		 6nm4B-3db2A:
21.86