SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 1hsgB-3dbgA:
undetectable		 1hsgB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.95A 1hshC-3dbgA:
undetectable		 1hshC-3dbgA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 1ohrA-3dbgA:
undetectable		 1ohrA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 1rl8A-3dbgA:
undetectable		 1rl8A-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 1rl8B-3dbgA:
undetectable		 1rl8B-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 1sdtB-3dbgA:
undetectable		 1sdtB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.85A 1sduB-3dbgA:
undetectable		 1sduB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.81A 1sdvB-3dbgA:
undetectable		 1sdvB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 6 LEU A 226
LEU A 245
LEU A 272
ILE A 264
 None
 0.93A 1z95A-3dbgA:
undetectable		 1z95A-3dbgA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 10 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.89A 2aquA-3dbgA:
undetectable		 2aquA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.90A 2aquB-3dbgA:
undetectable		 2aquB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 2avoB-3dbgA:
undetectable		 2avoB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 2avsB-3dbgA:
undetectable		 2avsB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 2b60A-3dbgA:
undetectable		 2b60A-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 2f80A-3dbgA:
undetectable		 2f80A-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.82A 2f80B-3dbgA:
undetectable		 2f80B-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2f81A-3dbgA:
undetectable		 2f81A-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2f81B-3dbgA:
undetectable		 2f81B-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.81A 2fxeB-3dbgA:
undetectable		 2fxeB-3dbgA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 LEU A 187
VAL A 227
HIS A 265
ALA A 166
VAL A 269
 None
None
None
HEM  A 500 ( 4.4A)
None
 1.39A 2g70A-3dbgA:
undetectable		 2g70A-3dbgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 LEU A 187
VAL A 227
HIS A 265
ALA A 166
VAL A 269
 None
None
None
HEM  A 500 ( 4.4A)
None
 1.40A 2g70B-3dbgA:
undetectable		 2g70B-3dbgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 LEU A 187
VAL A 227
HIS A 265
ALA A 166
VAL A 269
 None
None
None
HEM  A 500 ( 4.4A)
None
 1.36A 2g72A-3dbgA:
undetectable		 2g72A-3dbgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 2hs1A-3dbgA:
undetectable		 2hs1A-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.78A 2hs2A-3dbgA:
undetectable		 2hs2A-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.91A 2hs2B-3dbgA:
undetectable		 2hs2B-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.95A 2ienB-3dbgA:
undetectable		 2ienB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 2nmyA-3dbgA:
undetectable		 2nmyA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		3 / 3 VAL A 318
GLU A 136
GLU A 316
 None
 0.70A 2nv4A-3dbgA:
undetectable		 2nv4A-3dbgA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.85A 2o4kB-3dbgA:
undetectable		 2o4kB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.86A 2o4sA-3dbgA:
undetectable		 2o4sA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2o4sB-3dbgA:
undetectable		 2o4sB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.95A 2pymA-3dbgA:
undetectable		 2pymA-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.95A 2pynA-3dbgA:
undetectable		 2pynA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.94A 2q64A-3dbgA:
undetectable		 2q64A-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.92A 2qhcB-3dbgA:
undetectable		 2qhcB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 2r5pB-3dbgA:
undetectable		 2r5pB-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 2r5pD-3dbgA:
undetectable		 2r5pD-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2r5qB-3dbgA:
undetectable		 2r5qB-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 10 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2r5qD-3dbgA:
undetectable		 2r5qD-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 2rkfA-3dbgA:
undetectable		 2rkfA-3dbgA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.89A 2rkgB-3dbgA:
undetectable		 2rkgB-3dbgA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.94A 2z54A-3dbgA:
undetectable		 2z54A-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.93A 2z54B-3dbgA:
undetectable		 2z54B-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 3bvbB-3dbgA:
undetectable		 3bvbB-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 9 LEU A 286
TRP A 146
ALA A 426
MET A 417
GLN A 419
 None
None
None
None
HEM  A 500 ( 4.7A)
 1.09A 3cldA-3dbgA:
1.6		 3cldA-3dbgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.89A 3cywA-3dbgA:
undetectable		 3cywA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 3cywB-3dbgA:
undetectable		 3cywB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.75A 3cyxA-3dbgA:
undetectable		 3cyxA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 3d1zB-3dbgA:
undetectable		 3d1zB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 3d20B-3dbgA:
undetectable		 3d20B-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.75A 3ekqA-3dbgA:
undetectable		 3ekqA-3dbgA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 3ektC-3dbgA:
undetectable		 3ektC-3dbgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.86A 3ektD-3dbgA:
undetectable		 3ektD-3dbgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.96A 3ekwB-3dbgA:
undetectable		 3ekwB-3dbgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 10 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.82A 3ekyA-3dbgA:
undetectable		 3ekyA-3dbgA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 8 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.78A 3el0A-3dbgA:
undetectable		 3el0A-3dbgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 3em4A-3dbgA:
undetectable		 3em4A-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.86A 3em4U-3dbgA:
undetectable		 3em4U-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		3 / 3 MET A 417
CYH A 410
PRO A 402
 None
HEM  A 500 (-2.3A)
None
 1.21A 3h52C-3dbgA:
1.4		 3h52C-3dbgA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 3jvyA-3dbgA:
undetectable		 3jvyA-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.86A 3jw2A-3dbgA:
undetectable		 3jw2A-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.75A 3k4vA-3dbgA:
undetectable		 3k4vA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.90A 3k4vD-3dbgA:
undetectable		 3k4vD-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 3lzsA-3dbgA:
undetectable		 3lzsA-3dbgA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.89A 3lzsB-3dbgA:
undetectable		 3lzsB-3dbgA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.85A 3lzuA-3dbgA:
undetectable		 3lzuA-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.85A 3lzuB-3dbgA:
undetectable		 3lzuB-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.78A 3mwsA-3dbgA:
undetectable		 3mwsA-3dbgA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.90A 3nduA-3dbgA:
undetectable		 3nduA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.90A 3nduB-3dbgA:
undetectable		 3nduB-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.95A 3nduD-3dbgA:
undetectable		 3nduD-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 3oxxA-3dbgA:
undetectable		 3oxxA-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.63A 3oxxC-3dbgA:
undetectable		 3oxxC-3dbgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.93A 3pwrA-3dbgA:
undetectable		 3pwrA-3dbgA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.82A 3s54B-3dbgA:
undetectable		 3s54B-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 3tkgA-3dbgA:
undetectable		 3tkgA-3dbgA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.91A 3tkgC-3dbgA:
undetectable		 3tkgC-3dbgA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 10 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.81A 3ttpA-3dbgA:
undetectable		 3ttpA-3dbgA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 10 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 3ttpB-3dbgA:
undetectable		 3ttpB-3dbgA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		3 / 3 ARG A 371
ASP A 292
GLN A 435
 None
 0.85A 4azsA-3dbgA:
undetectable		 4azsA-3dbgA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 8 GLY A 359
ALA A 360
ASP A 361
PRO A  24
 None
 0.54A 4eyrB-3dbgA:
undetectable		 4eyrB-3dbgA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 8 VAL A 161
ILE A 283
SER A 276
ALA A 337
 None
 0.99A 4eyzA-3dbgA:
undetectable		 4eyzA-3dbgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 8 VAL A 161
ILE A 283
SER A 276
ALA A 337
 None
 1.00A 4eyzB-3dbgA:
undetectable		 4eyzB-3dbgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.83A 4hlaA-3dbgA:
undetectable		 4hlaA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 11 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.85A 4hlaB-3dbgA:
undetectable		 4hlaB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 8 VAL A 340
TRP A 339
LEU A  62
LEU A  40
 None
 1.06A 4jtrA-3dbgA:
undetectable		 4jtrA-3dbgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 5 PHE A 191
THR A 278
PHE A 159
ILE A 447
 None
HEM  A 500 (-4.2A)
None
None
 1.05A 4jx1E-3dbgA:
30.1		 4jx1E-3dbgA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		3 / 3 ASP A  43
TRP A 285
SER A  49
 None
 0.93A 4lrhA-3dbgA:
undetectable		 4lrhA-3dbgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.93A 4njvA-3dbgA:
undetectable		 4njvA-3dbgA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 7 LEU A 226
LEU A 245
LEU A 272
ILE A 264
 None
 0.93A 4okwA-3dbgA:
1.8		 4okwA-3dbgA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.90A 5e5kB-3dbgA:
undetectable		 5e5kB-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 6 VAL A 327
HIS A 296
HIS A 293
LEU A 290
 None
 1.36A 5hrqH-3dbgA:
undetectable
5hrqK-3dbgA:
undetectable
5hrqL-3dbgA:
undetectable		 5hrqH-3dbgA:
4.75
5hrqK-3dbgA:
3.41
5hrqL-3dbgA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 5t2zA-3dbgA:
undetectable		 5t2zA-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.87A 5t2zB-3dbgA:
undetectable		 5t2zB-3dbgA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.86A 5t8hA-3dbgA:
undetectable		 5t8hA-3dbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		3 / 3 LEU A 245
VAL A 227
ASP A 228
 None
 0.56A 5x23A-3dbgA:
33.3		 5x23A-3dbgA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		4 / 8 LEU A 272
VAL A 268
MET A 176
ILE A 230
 None
 0.75A 5y9mA-3dbgA:
undetectable		 5y9mA-3dbgA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.88A 6dgxA-3dbgA:
undetectable		 6dgxA-3dbgA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3dbg PUTATIVE CYTOCHROME
P450
(Streptomyces
coelicolor) 		5 / 12 GLY A 359
ALA A 360
ASP A 361
PRO A  24
ILE A 356
 None
 0.84A 6dj1A-3dbgA:
undetectable		 6dj1A-3dbgA:
9.38