SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 10 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.34A 1a52B-3dbiA:
undetectable		 1a52B-3dbiA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 8 ALA A 122
LEU A  66
LEU A  64
LEU A 308
 None
 0.78A 1e7cA-3dbiA:
undetectable		 1e7cA-3dbiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 9 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.31A 1ereA-3dbiA:
undetectable		 1ereA-3dbiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 9 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.31A 1ereB-3dbiA:
undetectable		 1ereB-3dbiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 9 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.31A 1ereC-3dbiA:
undetectable		 1ereC-3dbiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 9 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.30A 1ereD-3dbiA:
undetectable		 1ereD-3dbiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 7 LEU A  81
ILE A 301
ALA A  85
ILE A 309
 None
 0.83A 1oniB-3dbiA:
undetectable
1oniC-3dbiA:
undetectable		 1oniB-3dbiA:
18.32
1oniC-3dbiA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 10 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.48A 1qkuA-3dbiA:
undetectable		 1qkuA-3dbiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 10 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.48A 1qkuB-3dbiA:
undetectable		 1qkuB-3dbiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 10 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.48A 1qkuC-3dbiA:
undetectable		 1qkuC-3dbiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 5 HIS A 262
VAL A 233
GLY A 256
ALA A 230
 None
 0.93A 5hwaA-3dbiA:
undetectable		 5hwaA-3dbiA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 6 ARG A 154
LEU A 153
ARG A 152
ARG A 151
 None
None
None
PO4  A 339 (-2.7A)
 1.24A 5l6eA-3dbiA:
1.9
5l6eB-3dbiA:
undetectable		 5l6eA-3dbiA:
20.88
5l6eB-3dbiA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 9 ILE A 112
VAL A 148
ASN A 156
ASP A 137
ILE A 139
 None
 1.42A 5lg3D-3dbiA:
undetectable		 5lg3D-3dbiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		6 / 12 LEU A 308
ILE A 304
LEU A  64
LEU A  96
LEU A 149
MET A 124
 None
 1.22A 5nfjA-3dbiA:
undetectable		 5nfjA-3dbiA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 5 MET A 124
ASN A  70
VAL A  68
LEU A  66
 None
 1.33A 5xdhB-3dbiA:
0.0		 5xdhB-3dbiA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		4 / 5 MET A 124
ASN A  70
VAL A  68
LEU A  66
 None
 1.15A 5xdhD-3dbiA:
undetectable		 5xdhD-3dbiA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 11 ILE A 305
ALA A  86
LEU A  66
LEU A 149
ILE A 301
 GOL  A 340 ( 4.1A)
None
None
None
None
 1.03A 5z6mA-3dbiA:
undetectable		 5z6mA-3dbiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 10 ALA A 172
GLU A 175
LEU A 327
ILE A 295
HIS A 165
 None
 1.31A 6cbzB-3dbiA:
undetectable		 6cbzB-3dbiA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY
(Escherichia
coli) 		5 / 12 ILE A 184
SER A 273
GLY A 180
ALA A 179
ILE A 275
 None
 1.10A 6dwnD-3dbiA:
undetectable		 6dwnD-3dbiA:
12.54