SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 160
ALA A 165
THR A 147
SER A 167
 None
None
None
ZN  A 302 ( 4.8A)
 0.88A 1c9sT-3dbkA:
undetectable
1c9sU-3dbkA:
undetectable		 1c9sT-3dbkA:
12.75
1c9sU-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 160
ALA A 165
THR A 147
SER A 167
 None
None
None
ZN  A 302 ( 4.8A)
 0.82A 1gtfL-3dbkA:
undetectable
1gtfM-3dbkA:
undetectable		 1gtfL-3dbkA:
12.75
1gtfM-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 160
ALA A 165
THR A 147
SER A 167
 None
None
None
ZN  A 302 ( 4.8A)
 0.80A 1gtfN-3dbkA:
undetectable
1gtfO-3dbkA:
undetectable		 1gtfN-3dbkA:
12.75
1gtfO-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 11 ILE A 220
HIS A 223
GLY A 157
SER A 159
LEU A 153
 None
RDF  A2001 (-3.5A)
None
None
None
 1.43A 1kyvA-3dbkA:
undetectable
1kyvB-3dbkA:
undetectable		 1kyvA-3dbkA:
19.27
1kyvB-3dbkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 4 ASP A 168
HIS A 140
ARG A 198
GLU A 164
 None
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.6A)
ZN  A 302 ( 2.2A)
 0.98A 1lqtA-3dbkA:
undetectable		 1lqtA-3dbkA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.23A 1v7zA-3dbkA:
undetectable		 1v7zA-3dbkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.23A 1v7zB-3dbkA:
undetectable		 1v7zB-3dbkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.23A 1v7zC-3dbkA:
undetectable		 1v7zC-3dbkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 113
HIS A 140
GLU A 141
HIS A 144
GLU A 164
 RDF  A2001 (-4.3A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
ZN  A 302 ( 3.2A)
ZN  A 302 ( 2.2A)
 0.30A 2c6nA-3dbkA:
6.8		 2c6nA-3dbkA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 286
THR A 287
PHE A 290
THR A 296
 None
 1.25A 2kotA-3dbkA:
undetectable		 2kotA-3dbkA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 248
SER A 134
PHE A 166
ILE A 190
 None
 1.22A 2v0mD-3dbkA:
undetectable		 2v0mD-3dbkA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 179
ASP A 189
ILE A 190
GLU A 175
 None
None
None
CA  A 303 (-2.2A)
 1.24A 2xrzA-3dbkA:
undetectable
2xrzB-3dbkA:
undetectable		 2xrzA-3dbkA:
22.57
2xrzB-3dbkA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.18A 3a6jA-3dbkA:
undetectable		 3a6jA-3dbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 7 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.17A 3a6jB-3dbkA:
undetectable		 3a6jB-3dbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.17A 3a6jC-3dbkA:
undetectable		 3a6jC-3dbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.19A 3a6jE-3dbkA:
undetectable		 3a6jE-3dbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 8 GLU A 164
HIS A 140
HIS A 223
HIS A 144
GLU A 141
 ZN  A 302 ( 2.2A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-3.5A)
ZN  A 302 ( 3.2A)
RDF  A2001 (-2.7A)
 1.18A 3a6jF-3dbkA:
undetectable		 3a6jF-3dbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  56
PHE A  54
ASP A  41
VAL A 104
HIS A 105
 None
 1.17A 3dlcA-3dbkA:
undetectable		 3dlcA-3dbkA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 272
ALA A 269
GLY A 268
ALA A 213
LEU A 236
 None
 1.14A 3qxyA-3dbkA:
undetectable		 3qxyA-3dbkA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 272
ALA A 269
GLY A 268
ALA A 213
LEU A 236
 None
 1.09A 3rc0A-3dbkA:
1.4		 3rc0A-3dbkA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 272
ALA A 269
GLY A 268
ALA A 213
LEU A 236
 None
 1.09A 3rc0B-3dbkA:
undetectable		 3rc0B-3dbkA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 144
GLU A 164
ASP A 168
SER A 226
 ZN  A 302 ( 3.2A)
ZN  A 302 ( 2.2A)
None
None
 0.72A 4apjA-3dbkA:
6.3
4apjP-3dbkA:
undetectable		 4apjA-3dbkA:
20.65
4apjP-3dbkA:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 248
ALA A 173
ALA A 139
LEU A  86
 None
 0.88A 4dtzA-3dbkA:
undetectable		 4dtzA-3dbkA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 6 PHE A 248
ALA A 170
PRO A  95
LEU A  86
VAL A  83
 None
 1.50A 4dubB-3dbkA:
undetectable		 4dubB-3dbkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 6 PHE A 248
ALA A 173
PRO A  95
LEU A  86
VAL A  83
 None
 1.27A 4dubB-3dbkA:
undetectable		 4dubB-3dbkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 137
ASP A 136
GLY A 187
ALA A 113
 RDF  A2001 ( 4.2A)
CA  A 303 (-3.7A)
None
RDF  A2001 (-4.3A)
 0.82A 4m48A-3dbkA:
undetectable		 4m48A-3dbkA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 196
LEU A 185
ARG A 205
GLY A 171
HIS A 140
 None
None
None
None
ZN  A 302 ( 3.2A)
 1.37A 5dxbA-3dbkA:
undetectable		 5dxbA-3dbkA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.81A 5eevL-3dbkA:
undetectable
5eevV-3dbkA:
undetectable		 5eevL-3dbkA:
12.75
5eevV-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.81A 5eewL-3dbkA:
undetectable
5eewV-3dbkA:
undetectable		 5eewL-3dbkA:
12.75
5eewV-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.81A 5eezL-3dbkA:
undetectable
5eezV-3dbkA:
undetectable		 5eezL-3dbkA:
12.75
5eezV-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.81A 5ef1L-3dbkA:
undetectable
5ef1V-3dbkA:
undetectable		 5ef1L-3dbkA:
12.75
5ef1V-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.81A 5ef2L-3dbkA:
undetectable
5ef2V-3dbkA:
undetectable		 5ef2L-3dbkA:
12.75
5ef2V-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 147
SER A 167
GLY A 160
ALA A 165
 None
ZN  A 302 ( 4.8A)
None
None
 0.80A 5ef3L-3dbkA:
undetectable
5ef3V-3dbkA:
undetectable		 5ef3L-3dbkA:
12.75
5ef3V-3dbkA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A  90
GLU A 249
ASP A 243
 None
 1.01A 5gqbA-3dbkA:
undetectable		 5gqbA-3dbkA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 265
VAL A 295
PRO A 298
ALA A 269
 None
 1.14A 5otrA-3dbkA:
undetectable		 5otrA-3dbkA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.02A 5vooA-3dbkA:
undetectable		 5vooA-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.00A 5vooC-3dbkA:
undetectable		 5vooC-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.02A 5vooE-3dbkA:
undetectable		 5vooE-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.06A 5vooF-3dbkA:
undetectable		 5vooF-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.02A 5vopA-3dbkA:
undetectable		 5vopA-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 172
ASP A 168
GLY A 187
ARG A 179
ILE A 186
 CA  A 303 (-2.8A)
None
None
None
None
 1.03A 5vopB-3dbkA:
undetectable		 5vopB-3dbkA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 196
LEU A 185
ARG A 205
GLY A 171
HIS A 140
 None
None
None
None
ZN  A 302 ( 3.2A)
 1.36A 5wgqA-3dbkA:
undetectable		 5wgqA-3dbkA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 6 MET A 169
ALA A 289
LEU A 236
ALA A 237
 None
 1.10A 6fosB-3dbkA:
undetectable		 6fosB-3dbkA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dbk ELASTASE
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 221
ARG A 198
HIS A 224
ASP A 168
 RDF  A2001 ( 4.7A)
RDF  A2001 (-2.6A)
None
None
 0.98A 6mn4A-3dbkA:
undetectable		 6mn4A-3dbkA:
20.62