SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		3 / 3 LEU A  20
HIS A  85
ILE A  81
 None
 0.71A 1s9pB-3dbxA:
undetectable		 1s9pB-3dbxA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		4 / 7 PHE A 214
LEU A 242
VAL A 221
ILE A 219
 None
 0.99A 1t87B-3dbxA:
undetectable		 1t87B-3dbxA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		5 / 9 PHE A 214
LEU A 242
GLY A 239
VAL A 221
ILE A 219
 None
 1.32A 2a1oB-3dbxA:
undetectable		 2a1oB-3dbxA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		4 / 5 LEU A  43
SER A  71
ARG A  78
LEU A  50
 None
 1.16A 3onnA-3dbxA:
undetectable		 3onnA-3dbxA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		4 / 5 HIS A 102
LEU A 107
TRP A 114
LEU A  35
 None
 1.28A 4aqlA-3dbxA:
undetectable		 4aqlA-3dbxA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 241
TYR A 249
GLN A 250
 None
 0.68A 5qgkA-3dbxA:
undetectable		 5qgkA-3dbxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 241
TYR A 249
GLN A 250
 None
 0.64A 5qgrA-3dbxA:
undetectable		 5qgrA-3dbxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		3 / 3 VAL A 241
TYR A 249
GLN A 250
 None
 0.69A 5qgtA-3dbxA:
undetectable		 5qgtA-3dbxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3dbx CD1-2 ANTIGEN
(Gallus
gallus) 		4 / 4 LEU A 206
LEU A 256
SER A 237
ALA A 235
 None
 0.95A 5uunA-3dbxA:
undetectable		 5uunA-3dbxA:
20.12