SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.85A 1v55N-3dbyA:
1.8
1v55W-3dbyA:
undetectable		 1v55N-3dbyA:
17.09
1v55W-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.83A 2eijN-3dbyA:
1.8
2eijW-3dbyA:
undetectable		 2eijN-3dbyA:
17.09
2eijW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 7 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.82A 2eikA-3dbyA:
3.1
2eikJ-3dbyA:
undetectable		 2eikA-3dbyA:
17.09
2eikJ-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.84A 2eikN-3dbyA:
1.8
2eikW-3dbyA:
undetectable		 2eikN-3dbyA:
17.09
2eikW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.83A 2eilN-3dbyA:
2.9
2eilW-3dbyA:
undetectable		 2eilN-3dbyA:
17.09
2eilW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.80A 2einA-3dbyA:
2.8
2einJ-3dbyA:
undetectable		 2einA-3dbyA:
17.09
2einJ-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.86A 3abkA-3dbyA:
4.3
3abkJ-3dbyA:
undetectable		 3abkA-3dbyA:
17.09
3abkJ-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.76A 3ablN-3dbyA:
1.9
3ablW-3dbyA:
undetectable		 3ablN-3dbyA:
17.09
3ablW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.82A 3abmN-3dbyA:
1.9
3abmW-3dbyA:
undetectable		 3abmN-3dbyA:
17.09
3abmW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.88A 3ag3N-3dbyA:
1.8
3ag3W-3dbyA:
undetectable		 3ag3N-3dbyA:
17.09
3ag3W-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.85A 3asnN-3dbyA:
2.0
3asnW-3dbyA:
undetectable		 3asnN-3dbyA:
17.09
3asnW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.80A 3asoN-3dbyA:
1.9
3asoW-3dbyA:
undetectable		 3asoN-3dbyA:
17.09
3asoW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6D_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 6 PHE A  12
VAL A 114
TRP A  17
PRO A 259
 None
 1.45A 3n6dA-3dbyA:
undetectable
3n6dB-3dbyA:
undetectable		 3n6dA-3dbyA:
19.30
3n6dB-3dbyA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 4 ILE A  84
LEU A  81
LYS A  80
ASN A 102
 None
 1.35A 4g19D-3dbyA:
undetectable		 4g19D-3dbyA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 PRO A 124
VAL A 123
ASN A   5
GLN A 248
 None
 1.08A 4iilA-3dbyA:
undetectable		 4iilA-3dbyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 7 GLU A  13
TYR A 132
LEU A 246
TYR A 241
 None
 1.14A 4twdF-3dbyA:
3.1
4twdJ-3dbyA:
undetectable		 4twdF-3dbyA:
18.71
4twdJ-3dbyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		5 / 12 PHE A 100
ILE A 101
MET A 231
ALA A  33
ILE A  94
 None
 1.33A 5mlmA-3dbyA:
undetectable		 5mlmA-3dbyA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 6 ILE A  92
ALA A  33
LEU A  32
ILE A  40
 None
 0.81A 5mvmB-3dbyA:
5.6
5mvmC-3dbyA:
5.4		 5mvmB-3dbyA:
11.97
5mvmC-3dbyA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		5 / 12 MET A 235
ALA A 229
GLU A 213
LEU A 211
VAL A 223
 None
 1.49A 5vlmH-3dbyA:
2.4		 5vlmH-3dbyA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		5 / 12 PHE A 207
ALA A 144
GLY A 150
ALA A 236
VAL A 214
 None
 0.97A 5w4zA-3dbyA:
undetectable		 5w4zA-3dbyA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		5 / 12 PHE A 207
ALA A 144
GLY A 150
ALA A 236
VAL A 214
 None
 0.98A 5w4zB-3dbyA:
undetectable		 5w4zB-3dbyA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.86A 5xdxN-3dbyA:
1.9
5xdxW-3dbyA:
undetectable		 5xdxN-3dbyA:
17.09
5xdxW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.84A 5zcpN-3dbyA:
2.1
5zcpW-3dbyA:
undetectable		 5zcpN-3dbyA:
17.09
5zcpW-3dbyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dby UNCHARACTERIZED
PROTEIN
(Bacillus
cereus) 		4 / 8 LEU A  53
PHE A  50
ARG A  77
LEU A 115
 None
 0.89A 5zcqN-3dbyA:
2.1
5zcqW-3dbyA:
undetectable		 5zcqN-3dbyA:
17.09
5zcqW-3dbyA:
12.45