SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 9 LEU A  46
ILE A  45
LEU A 180
VAL A 211
GLY A 208
 None
 1.18A 1e7aA-3dc7A:
undetectable		 1e7aA-3dc7A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 9 LEU A  46
ILE A  45
LEU A 180
VAL A 211
GLY A 208
 None
 1.22A 1e7aB-3dc7A:
undetectable		 1e7aB-3dc7A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		4 / 7 GLN A  99
THR A  64
SER A  67
TYR A  69
 None
 1.28A 1eiiA-3dc7A:
undetectable		 1eiiA-3dc7A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		6 / 10 GLY A  66
ALA A  71
ASP A  70
ILE A  60
GLY A  28
VAL A  88
 None
 1.35A 3oxwC-3dc7A:
undetectable		 3oxwC-3dc7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 12 GLY A  96
PHE A 148
TYR A  69
ASN A  35
LEU A 202
 None
 1.44A 4a83A-3dc7A:
undetectable		 4a83A-3dc7A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		4 / 8 SER A  63
ARG A  75
ASN A  93
ASP A  94
 None
 1.12A 4d39A-3dc7A:
undetectable		 4d39A-3dc7A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		6 / 12 GLY A  59
ALA A  33
SER A  61
ILE A  79
TYR A  76
ASP A  70
 None
 1.36A 4rtpA-3dc7A:
3.9		 4rtpA-3dc7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 12 ILE A  79
PRO A  80
ASP A  82
ALA A  83
ILE A  86
 None
 1.06A 4uroC-3dc7A:
undetectable		 4uroC-3dc7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		4 / 5 THR A  32
HIS A  41
ALA A  33
ASP A  29
 None
 1.10A 5mfxA-3dc7A:
undetectable		 5mfxA-3dc7A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		4 / 7 VAL A 199
HIS A 209
PRO A 204
ILE A 212
 None
 1.23A 5vkqC-3dc7A:
undetectable
5vkqD-3dc7A:
undetectable		 5vkqC-3dc7A:
8.88
5vkqD-3dc7A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 11 TYR A  42
ASP A  56
HIS A  43
THR A  32
GLY A  59
 None
 1.49A 6mb5A-3dc7A:
undetectable		 6mb5A-3dc7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 10 TYR A  42
ASP A  56
HIS A  43
THR A  32
GLY A  59
 None
 1.49A 6mb9A-3dc7A:
undetectable		 6mb9A-3dc7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 10 TYR A  42
ASP A  56
HIS A  43
THR A  32
GLY A  59
 None
 1.48A 6mb9B-3dc7A:
undetectable		 6mb9B-3dc7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 10 TYR A  42
ASP A  56
HIS A  43
THR A  32
GLY A  59
 None
 1.49A 6mb9C-3dc7A:
undetectable		 6mb9C-3dc7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323
(Lactobacillus
plantarum) 		5 / 10 TYR A  42
ASP A  56
HIS A  43
THR A  32
GLY A  59
 None
 1.49A 6mb9D-3dc7A:
undetectable		 6mb9D-3dc7A:
19.71