SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 4 HIS A 169
LEU A  74
LEU A  70
LEU A  87
 CL  A 216 (-4.1A)
None
None
None
 1.13A 1a4lD-3dciA:
undetectable		 1a4lD-3dciA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 4 GLY A  47
LEU A  48
GLY A   8
ARG A  51
 None
 1.44A 1j7kA-3dciA:
undetectable		 1j7kA-3dciA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 175
ALA A 157
LEU A 156
ALA A 192
ASP A 189
 None
 1.19A 2yvlD-3dciA:
3.7		 2yvlD-3dciA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  50
ASP A  91
LEU A  48
THR A  12
THR A 193
 ACY  A 220 (-3.7A)
None
None
None
None
 1.06A 3eeyC-3dciA:
2.8		 3eeyC-3dciA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  50
ASP A  91
LEU A  48
THR A  12
THR A 193
 ACY  A 220 (-3.7A)
None
None
None
None
 0.99A 3eeyE-3dciA:
4.1		 3eeyE-3dciA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  50
ASP A  91
LEU A  48
THR A  12
THR A 193
 ACY  A 220 (-3.7A)
None
None
None
None
 1.01A 3eeyF-3dciA:
4.2		 3eeyF-3dciA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 168
ALA A 164
ILE A 130
ILE A  84
LEU A  82
 None
 0.91A 4dt8A-3dciA:
undetectable		 4dt8A-3dciA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 8 LEU A  37
ILE A  84
VAL A 131
GLY A 197
 None
 0.93A 4eq4B-3dciA:
undetectable		 4eq4B-3dciA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 VAL A 114
ALA A   6
LEU A 129
LEU A 128
LEU A  87
 None
 1.18A 4i1rA-3dciA:
4.1		 4i1rA-3dciA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 6 ARG A  28
GLY A  14
ASP A  31
PRO A  30
 None
 1.21A 4lajA-3dciA:
undetectable
4lajB-3dciA:
undetectable		 4lajA-3dciA:
19.74
4lajB-3dciA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 ALA A  69
GLY A   8
THR A  12
LEU A  11
GLY A  49
 None
None
None
ACY  A 220 ( 4.9A)
ACY  A 220 ( 3.8A)
 0.80A 4n48B-3dciA:
2.9		 4n48B-3dciA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 5 GLY A  49
ASP A   9
GLU A  46
VAL A  83
 ACY  A 220 ( 3.8A)
ACY  A 220 (-3.6A)
None
None
 0.82A 4nkvD-3dciA:
undetectable		 4nkvD-3dciA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 8 LEU A  74
LEU A   5
VAL A  83
ILE A  85
 None
 0.93A 4oj4A-3dciA:
undetectable		 4oj4A-3dciA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		5 / 12 VAL A  72
GLU A  71
LEU A  48
ALA A  69
LEU A 110
 None
 1.28A 5nd4B-3dciA:
4.9		 5nd4B-3dciA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 5 THR A  89
THR A 193
HIS A  23
GLY A   8
 ACY  A 220 ( 4.2A)
None
None
None
 1.15A 6gbnC-3dciA:
5.8		 6gbnC-3dciA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3dci ARYLESTERASE
(Agrobacterium
fabrum) 		4 / 5 THR A  89
THR A 193
HIS A  23
GLY A  49
 ACY  A 220 ( 4.2A)
None
None
ACY  A 220 ( 3.8A)
 1.08A 6gbnC-3dciA:
5.8		 6gbnC-3dciA:
20.81