SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A  40
HIS A 260
ASP A 264
HIS A 123
ASP A 258
 ZN  A 301 (-3.5A)
ZN  A 301 (-3.4A)
None
FE  A 310 (-3.3A)
FE  A 311 (-2.6A)
 1.15A 1a4lC-3dcpA:
9.1		 1a4lC-3dcpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 6 HIS A   6
HIS A   8
HIS A 123
HIS A 181
ASP A 258
 FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-2.6A)
 0.95A 1fweC-3dcpA:
5.4		 1fweC-3dcpA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		6 / 12 GLU A  93
HIS A 123
HIS A   6
ASN A 224
TYR A 237
ASP A 258
 FE  A 311 ( 2.6A)
FE  A 310 (-3.3A)
FE  A 311 (-3.3A)
None
None
FE  A 311 (-2.6A)
 1.28A 1ituA-3dcpA:
7.5		 1ituA-3dcpA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 GLU A  93
HIS A 123
HIS A   6
TYR A 237
ASP A 258
 FE  A 311 ( 2.6A)
FE  A 310 (-3.3A)
FE  A 311 (-3.3A)
None
FE  A 311 (-2.6A)
 1.45A 1ituA-3dcpA:
7.5		 1ituA-3dcpA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 GLU A  93
HIS A 123
HIS A   6
TYR A 237
ASP A 258
 FE  A 311 ( 2.6A)
FE  A 310 (-3.3A)
FE  A 311 (-3.3A)
None
FE  A 311 (-2.6A)
 1.24A 1ituB-3dcpA:
4.3		 1ituB-3dcpA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.89A 1mj2A-3dcpA:
undetectable
1mj2B-3dcpA:
undetectable		 1mj2A-3dcpA:
16.86
1mj2B-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.93A 1mj2C-3dcpA:
undetectable
1mj2D-3dcpA:
undetectable		 1mj2C-3dcpA:
16.86
1mj2D-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
PHE A 136
GLU A  56
ALA A  61
HIS A  40
 FE  A 310 (-3.3A)
None
None
None
ZN  A 301 (-3.5A)
 1.00A 1mjlA-3dcpA:
undetectable
1mjlB-3dcpA:
undetectable		 1mjlA-3dcpA:
16.86
1mjlB-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.93A 1mjoC-3dcpA:
undetectable
1mjoD-3dcpA:
undetectable		 1mjoC-3dcpA:
16.86
1mjoD-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 GLU A  56
HIS A  40
PRO A  13
HIS A 123
PHE A 136
 None
ZN  A 301 (-3.5A)
None
FE  A 310 (-3.3A)
None
 0.96A 1mjqA-3dcpA:
undetectable
1mjqB-3dcpA:
undetectable		 1mjqA-3dcpA:
16.86
1mjqB-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.89A 1mjqA-3dcpA:
undetectable
1mjqB-3dcpA:
undetectable		 1mjqA-3dcpA:
16.86
1mjqB-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
ALA A  61
HIS A  40
 FE  A 310 (-3.3A)
None
None
None
ZN  A 301 (-3.5A)
 0.88A 1mjqC-3dcpA:
undetectable
1mjqD-3dcpA:
undetectable		 1mjqC-3dcpA:
16.86
1mjqD-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.98A 1mjqC-3dcpA:
undetectable
1mjqD-3dcpA:
undetectable		 1mjqC-3dcpA:
16.86
1mjqD-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 10 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.90A 1mjqG-3dcpA:
undetectable
1mjqH-3dcpA:
undetectable		 1mjqG-3dcpA:
16.86
1mjqH-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 GLU A  56
HIS A  40
PRO A  13
HIS A 123
PHE A 136
 None
ZN  A 301 (-3.5A)
None
FE  A 310 (-3.3A)
None
 0.91A 1mjqI-3dcpA:
undetectable
1mjqJ-3dcpA:
undetectable		 1mjqI-3dcpA:
16.86
1mjqJ-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
ALA A  61
HIS A  40
 FE  A 310 (-3.3A)
None
None
None
ZN  A 301 (-3.5A)
 0.89A 1mjqI-3dcpA:
undetectable
1mjqJ-3dcpA:
undetectable		 1mjqI-3dcpA:
16.86
1mjqJ-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A 123
PHE A 136
GLU A  56
HIS A  40
PRO A  13
 FE  A 310 (-3.3A)
None
None
ZN  A 301 (-3.5A)
None
 0.99A 1mjqI-3dcpA:
undetectable
1mjqJ-3dcpA:
undetectable		 1mjqI-3dcpA:
16.86
1mjqJ-3dcpA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 10 GLY A   5
GLU A 220
GLY A 118
VAL A 254
HIS A 181
 None
None
None
None
FE  A 310 (-3.5A)
 1.34A 1pwyE-3dcpA:
undetectable		 1pwyE-3dcpA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 4 HIS A  40
GLU A  93
HIS A   8
HIS A 260
 ZN  A 301 (-3.5A)
FE  A 311 ( 2.6A)
FE  A 311 (-3.4A)
ZN  A 301 (-3.4A)
 1.16A 1utzB-3dcpA:
undetectable		 1utzB-3dcpA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.76A 1v55N-3dcpA:
undetectable
1v55W-3dcpA:
undetectable		 1v55N-3dcpA:
19.37
1v55W-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.75A 2eijN-3dcpA:
undetectable
2eijW-3dcpA:
undetectable		 2eijN-3dcpA:
19.37
2eijW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 7 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.78A 2eikA-3dcpA:
undetectable
2eikJ-3dcpA:
undetectable		 2eikA-3dcpA:
19.37
2eikJ-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.77A 2eikN-3dcpA:
undetectable
2eikW-3dcpA:
undetectable		 2eikN-3dcpA:
19.37
2eikW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.77A 2eilN-3dcpA:
undetectable
2eilW-3dcpA:
undetectable		 2eilN-3dcpA:
19.37
2eilW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.75A 2einA-3dcpA:
undetectable
2einJ-3dcpA:
undetectable		 2einA-3dcpA:
19.37
2einJ-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 4 HIS A  40
GLU A  93
HIS A   8
HIS A 260
 ZN  A 301 (-3.5A)
FE  A 311 ( 2.6A)
FE  A 311 (-3.4A)
ZN  A 301 (-3.4A)
 1.14A 2ow9B-3dcpA:
undetectable		 2ow9B-3dcpA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.16A 2zweA-3dcpA:
undetectable
2zweB-3dcpA:
undetectable		 2zweA-3dcpA:
22.64
2zweB-3dcpA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.18A 2zwfA-3dcpA:
undetectable
2zwfB-3dcpA:
undetectable		 2zwfA-3dcpA:
22.64
2zwfB-3dcpA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.19A 2zwgA-3dcpA:
undetectable
2zwgB-3dcpA:
undetectable		 2zwgA-3dcpA:
22.64
2zwgB-3dcpA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.73A 3abkA-3dcpA:
undetectable
3abkJ-3dcpA:
undetectable		 3abkA-3dcpA:
19.37
3abkJ-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.81A 3abmN-3dcpA:
undetectable
3abmW-3dcpA:
undetectable		 3abmN-3dcpA:
19.37
3abmW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 7 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.77A 3ag2N-3dcpA:
undetectable
3ag2W-3dcpA:
undetectable		 3ag2N-3dcpA:
19.37
3ag2W-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 7 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.78A 3ag4N-3dcpA:
undetectable
3ag4W-3dcpA:
undetectable		 3ag4N-3dcpA:
19.37
3ag4W-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.76A 3asnN-3dcpA:
undetectable
3asnW-3dcpA:
undetectable		 3asnN-3dcpA:
19.37
3asnW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.78A 3asoN-3dcpA:
undetectable
3asoW-3dcpA:
undetectable		 3asoN-3dcpA:
19.37
3asoW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		3 / 3 MET A 204
CYH A 185
PRO A 239
 None
 1.09A 3h52C-3dcpA:
undetectable		 3h52C-3dcpA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 4 HIS A  40
GLU A  93
HIS A   8
HIS A 260
 ZN  A 301 (-3.5A)
FE  A 311 ( 2.6A)
FE  A 311 (-3.4A)
ZN  A 301 (-3.4A)
 1.22A 3lilA-3dcpA:
undetectable		 3lilA-3dcpA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 HIS A   6
ASP A 258
HIS A 260
ASP A  95
LEU A  43
 FE  A 311 (-3.3A)
FE  A 311 (-2.6A)
ZN  A 301 (-3.4A)
None
None
 1.44A 3lmyA-3dcpA:
4.6		 3lmyA-3dcpA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 5 LEU A 184
HIS A  40
GLU A  93
HIS A   8
 None
ZN  A 301 (-3.5A)
FE  A 311 ( 2.6A)
FE  A 311 (-3.4A)
 1.26A 4a7bB-3dcpA:
undetectable		 4a7bB-3dcpA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 4 TYR A  71
THR A   7
VAL A  20
ILE A  90
 None
 1.00A 4jx1F-3dcpA:
undetectable		 4jx1F-3dcpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 7 HIS A 123
HIS A 181
HIS A   6
HIS A   8
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
 0.92A 4p6sB-3dcpA:
undetectable		 4p6sB-3dcpA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 GLY A 180
ASP A 222
PHE A 207
ILE A 182
HIS A 123
 None
None
None
None
FE  A 310 (-3.3A)
 1.36A 4wh5A-3dcpA:
undetectable		 4wh5A-3dcpA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 8 VAL A  38
HIS A 181
ASP A 258
HIS A 123
HIS A   8
 None
FE  A 310 (-3.5A)
FE  A 311 (-2.6A)
FE  A 310 (-3.3A)
FE  A 311 (-3.4A)
 1.46A 5a5zA-3dcpA:
undetectable		 5a5zA-3dcpA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 6 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.79A 5b1aN-3dcpA:
undetectable
5b1aW-3dcpA:
undetectable		 5b1aN-3dcpA:
19.37
5b1aW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 7 VAL A 243
ILE A 182
CYH A 233
PHE A 223
 None
 0.92A 5hieC-3dcpA:
undetectable		 5hieC-3dcpA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 ILE A  98
GLY A 162
ILE A 145
PHE A 148
TYR A 149
 None
 1.01A 5igwA-3dcpA:
undetectable		 5igwA-3dcpA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 4 HIS A  40
GLU A  93
HIS A   8
HIS A 260
 ZN  A 301 (-3.5A)
FE  A 311 ( 2.6A)
FE  A 311 (-3.4A)
ZN  A 301 (-3.4A)
 1.21A 5n5jA-3dcpA:
undetectable		 5n5jA-3dcpA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		3 / 3 HIS A  14
HIS A  40
HIS A   8
 ZN  A 301 (-3.5A)
ZN  A 301 (-3.5A)
FE  A 311 (-3.4A)
 0.97A 5oexA-3dcpA:
undetectable		 5oexA-3dcpA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 TYR A 237
VAL A 203
SER A 121
LEU A 122
GLN A 156
 None
None
FE  A 310 ( 4.1A)
None
None
 1.16A 5ubbA-3dcpA:
undetectable		 5ubbA-3dcpA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 9 ASP A   4
GLY A 256
ASN A 224
TYR A  35
ALA A  27
 None
 1.33A 5x66C-3dcpA:
undetectable		 5x66C-3dcpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 10 ASP A   4
GLY A 256
ASN A 224
TYR A  35
ALA A  27
 None
 1.31A 5x66D-3dcpA:
undetectable		 5x66D-3dcpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.74A 5xdxN-3dcpA:
undetectable
5xdxW-3dcpA:
undetectable		 5xdxN-3dcpA:
19.37
5xdxW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.14A 5z0gA-3dcpA:
undetectable
5z0gB-3dcpA:
undetectable		 5z0gA-3dcpA:
14.81
5z0gB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.17A 5z0hA-3dcpA:
undetectable
5z0hB-3dcpA:
undetectable		 5z0hA-3dcpA:
14.81
5z0hB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.17A 5z0iA-3dcpA:
undetectable
5z0iB-3dcpA:
undetectable		 5z0iA-3dcpA:
14.81
5z0iB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.17A 5z0jA-3dcpA:
undetectable
5z0jB-3dcpA:
undetectable		 5z0jA-3dcpA:
14.81
5z0jB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.16A 5z0kA-3dcpA:
undetectable
5z0kB-3dcpA:
undetectable		 5z0kA-3dcpA:
14.81
5z0kB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.19A 5z0lA-3dcpA:
undetectable
5z0lB-3dcpA:
undetectable		 5z0lA-3dcpA:
14.81
5z0lB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 11 HIS A 123
HIS A 181
HIS A   6
HIS A   8
ASP A 264
 FE  A 310 (-3.3A)
FE  A 310 (-3.5A)
FE  A 311 (-3.3A)
FE  A 311 (-3.4A)
None
 1.24A 5z0mA-3dcpA:
undetectable
5z0mB-3dcpA:
undetectable		 5z0mA-3dcpA:
15.19
5z0mB-3dcpA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.77A 5zcoA-3dcpA:
undetectable
5zcoJ-3dcpA:
undetectable		 5zcoA-3dcpA:
19.37
5zcoJ-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.74A 5zcpN-3dcpA:
undetectable
5zcpW-3dcpA:
undetectable		 5zcpN-3dcpA:
19.37
5zcpW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 LEU A  30
PHE A  32
TYR A 255
THR A 271
 None
 0.77A 5zcqN-3dcpA:
undetectable
5zcqW-3dcpA:
undetectable		 5zcqN-3dcpA:
19.37
5zcqW-3dcpA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		5 / 12 GLY A 127
GLU A 143
GLY A 144
GLY A 129
GLY A 130
 None
 0.79A 5zhmB-3dcpA:
undetectable		 5zhmB-3dcpA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 5 HIS A 260
CYH A  12
HIS A  14
HIS A  40
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.8A)
ZN  A 301 (-3.5A)
ZN  A 301 (-3.5A)
 1.21A 5zrdB-3dcpA:
undetectable		 5zrdB-3dcpA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		3 / 3 TYR A 159
HIS A 181
MET A 179
 None
FE  A 310 (-3.5A)
None
 0.79A 6af6A-3dcpA:
undetectable		 6af6A-3dcpA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 6 PHE A  92
GLY A  91
THR A 115
GLN A 114
 None
 0.87A 6ag0A-3dcpA:
4.9		 6ag0A-3dcpA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 6 PHE A  92
GLY A  91
THR A 115
GLN A 114
 None
 0.88A 6ag0C-3dcpA:
3.3		 6ag0C-3dcpA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 3dcp HISTIDINOL-PHOSPHATA
SE
(Listeria
monocytogenes) 		4 / 8 GLY A 180
GLY A 162
SER A 166
ALA A 169
 None
 0.78A 6hu9H-3dcpA:
undetectable
6hu9e-3dcpA:
undetectable		 6hu9H-3dcpA:
16.54
6hu9e-3dcpA:
19.64