SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 3dcz PUTATIVE RNFG
SUBUNIT OF ELECTRON
TRANSPORT COMPLEX
(Thermotoga
maritima) 		3 / 3 ARG A 217
TYR A  81
LYS A  79
 None
 0.92A 1uujB-3dczA:
undetectable		 1uujB-3dczA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3dcz PUTATIVE RNFG
SUBUNIT OF ELECTRON
TRANSPORT COMPLEX
(Thermotoga
maritima) 		4 / 7 VAL A  86
LYS A  79
TYR A  81
GLU A 220
 None
 1.11A 3hs4A-3dczA:
undetectable		 3hs4A-3dczA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3dcz PUTATIVE RNFG
SUBUNIT OF ELECTRON
TRANSPORT COMPLEX
(Thermotoga
maritima) 		5 / 12 PRO A 162
LEU A 166
ASN A 213
VAL A 209
PHE A 158
 None
 1.39A 3megA-3dczA:
undetectable		 3megA-3dczA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3dcz PUTATIVE RNFG
SUBUNIT OF ELECTRON
TRANSPORT COMPLEX
(Thermotoga
maritima) 		3 / 3 ARG A 157
LYS A 187
ARG A 156
 None
None
EDO  A   3 (-3.4A)
 1.29A 3w1wA-3dczA:
undetectable
3w1wB-3dczA:
undetectable		 3w1wA-3dczA:
22.35
3w1wB-3dczA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3dcz PUTATIVE RNFG
SUBUNIT OF ELECTRON
TRANSPORT COMPLEX
(Thermotoga
maritima) 		3 / 3 GLU A 220
GLY A 127
SER A 223
 None
 0.63A 4b53B-3dczA:
undetectable		 4b53B-3dczA:
22.84