SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dd4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3dd4 KV
CHANNEL-INTERACTING
PROTEIN 4
(Mus
musculus) 		5 / 12 LEU A 146
ILE A 209
ASN A 145
ILE A 149
ALA A 110
 None
 1.21A 2ejtA-3dd4A:
undetectable		 2ejtA-3dd4A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3dd4 KV
CHANNEL-INTERACTING
PROTEIN 4
(Mus
musculus) 		4 / 7 VAL A  16
LYS A  20
GLN A  24
GLY A  26
 None
 0.74A 3bjwB-3dd4A:
undetectable		 3bjwB-3dd4A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3dd4 KV
CHANNEL-INTERACTING
PROTEIN 4
(Mus
musculus) 		3 / 3 VAL A 203
GLY A 201
LYS A 157
 CA  A 404 ( 4.6A)
None
None
 0.77A 4k50A-3dd4A:
undetectable		 4k50A-3dd4A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3dd4 KV
CHANNEL-INTERACTING
PROTEIN 4
(Mus
musculus) 		3 / 3 VAL A 203
GLY A 201
LYS A 157
 CA  A 404 ( 4.6A)
None
None
 0.73A 4k50E-3dd4A:
0.8		 4k50E-3dd4A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3dd4 KV
CHANNEL-INTERACTING
PROTEIN 4
(Mus
musculus) 		3 / 3 TYR A  70
ARG A 133
SER A 129
 None
 0.97A 4khpI-3dd4A:
undetectable
4khpJ-3dd4A:
undetectable		 4khpI-3dd4A:
21.05
4khpJ-3dd4A:
17.47