SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ddc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3ddc RAS ASSOCIATION
DOMAIN-CONTAINING
FAMILY PROTEIN 5
(Mus
musculus) 		3 / 3 LYS B 355
VAL B 353
HIS B 238
 None
 1.21A 3tj7A-3ddcB:
undetectable		 3tj7A-3ddcB:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3ddc RAS ASSOCIATION
DOMAIN-CONTAINING
FAMILY PROTEIN 5
(Mus
musculus) 		3 / 3 PRO B 345
ARG B 340
GLU B 217
 None
 0.79A 5j6hA-3ddcB:
undetectable		 5j6hA-3ddcB:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 3ddc RAS ASSOCIATION
DOMAIN-CONTAINING
FAMILY PROTEIN 5
(Mus
musculus) 		5 / 11 ILE B 332
LEU B 330
LEU B 300
ILE B 287
MET B 285
 None
 1.42A 6fgcA-3ddcB:
undetectable		 6fgcA-3ddcB:
18.67