SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 12 TYR A  43
VAL A  30
ILE A  27
PHE A  26
VAL A 142
 None
 1.18A 1c9hA-3ddeA:
undetectable		 1c9hA-3ddeA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		4 / 4 LEU A 133
SER A 136
TYR A 137
LEU A 185
 None
 1.23A 1xz1A-3ddeA:
7.7		 1xz1A-3ddeA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		4 / 4 LEU A 133
SER A 136
TYR A 137
LEU A 185
 None
 1.24A 1xz3A-3ddeA:
7.6		 1xz3A-3ddeA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		3 / 3 THR A 113
PRO A 111
THR A 115
 None
 0.78A 209dC-3ddeA:
undetectable		 209dC-3ddeA:
3.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		4 / 5 PHE A  75
LEU A 185
VAL A 188
VAL A  61
 None
 1.23A 2m56A-3ddeA:
undetectable		 2m56A-3ddeA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		4 / 5 PHE A  26
PRO A 148
VAL A 104
PHE A 167
 None
 1.23A 2ygnA-3ddeA:
undetectable		 2ygnA-3ddeA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 12 GLN A 154
VAL A 149
LEU A 150
LEU A  31
GLY A 144
 None
 1.04A 3kk6B-3ddeA:
undetectable		 3kk6B-3ddeA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		4 / 8 PHE A 167
ALA A  90
PHE A 166
THR A 113
 None
 0.78A 3t3sD-3ddeA:
undetectable		 3t3sD-3ddeA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 12 TYR A  43
VAL A  30
ILE A  27
PHE A  26
VAL A 142
 None
 1.18A 5hkgA-3ddeA:
undetectable		 5hkgA-3ddeA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		3 / 3 VAL A 104
LEU A 159
MET A 164
 None
 0.86A 5ikrA-3ddeA:
0.1		 5ikrA-3ddeA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_A_GM4A301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 11 VAL A 142
ALA A 139
TRP A 138
TYR A  43
TYR A  50
 None
 1.27A 6dk1A-3ddeA:
0.0		 6dk1A-3ddeA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_B_GM4B301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 11 VAL A 142
ALA A 139
TRP A 138
TYR A  43
TYR A  50
 None
 1.26A 6dk1B-3ddeA:
undetectable		 6dk1B-3ddeA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 11 VAL A 142
ALA A 139
TRP A 138
TYR A  43
TYR A  50
 None
 1.25A 6dk1C-3ddeA:
undetectable		 6dk1C-3ddeA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD
(Shewanella
denitrificans) 		5 / 11 VAL A 142
ALA A 139
TRP A 138
TYR A  50
THR A  47
 None
 1.43A 6dk1C-3ddeA:
undetectable		 6dk1C-3ddeA:
23.22