SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ddm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 7 ARG A  71
THR A  75
VAL A  76
ALA A  17
 None
 1.09A 1fo4B-3ddmA:
undetectable		 1fo4B-3ddmA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 8 LEU A  77
VAL A  57
GLY A 119
LEU A  72
 None
 0.96A 1jlbA-3ddmA:
undetectable		 1jlbA-3ddmA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		6 / 12 LEU A  81
LEU A 124
GLY A 119
ASP A 121
ALA A 118
ALA A 114
 None
 1.31A 2br4F-3ddmA:
undetectable		 2br4F-3ddmA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 6 ARG A  71
THR A  75
VAL A  76
LEU A  77
 None
 1.02A 2e1qA-3ddmA:
1.6		 2e1qA-3ddmA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 6 ARG A  71
THR A  75
VAL A  76
LEU A  77
 None
 0.94A 2e1qC-3ddmA:
2.1		 2e1qC-3ddmA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		3 / 3 LEU A 195
LEU A 227
MET A 203
 None
 0.78A 2itzA-3ddmA:
undetectable		 2itzA-3ddmA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 8 LEU A 362
LEU A 355
VAL A 337
GLY A 336
 None
 0.88A 2po5B-3ddmA:
undetectable		 2po5B-3ddmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 5 ILE A 360
TYR A 171
ARG A 345
GLY A 336
 None
 1.11A 3b9mA-3ddmA:
undetectable		 3b9mA-3ddmA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 LEU A 234
ALA A 250
ALA A 204
VAL A 178
GLY A 209
 None
 1.11A 3c6gB-3ddmA:
undetectable		 3c6gB-3ddmA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 LEU A 352
VAL A 370
GLY A 369
ILE A 122
LEU A 316
 None
 1.10A 3ijdA-3ddmA:
6.3		 3ijdA-3ddmA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 LEU A 352
VAL A 370
GLY A 369
ILE A 122
LEU A 316
 None
 1.06A 3ijdB-3ddmA:
7.5		 3ijdB-3ddmA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 LEU A 136
SER A 319
PHE A 288
ILE A 122
ALA A 123
 None
 1.08A 3kk6A-3ddmA:
undetectable		 3kk6A-3ddmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		3 / 3 ASN A 155
ASN A 188
GLU A 160
 None
 0.85A 3kpdC-3ddmA:
undetectable		 3kpdC-3ddmA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		3 / 3 ASN A 155
ASN A 188
GLU A 160
 None
 0.75A 3kpdB-3ddmA:
undetectable		 3kpdB-3ddmA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 9 LEU A 124
VAL A  43
ILE A 117
ALA A 116
ALA A  78
 None
 1.20A 3mdtA-3ddmA:
undetectable		 3mdtA-3ddmA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 8 ASP A 338
ALA A 339
TYR A 150
TYR A 171
 None
 1.10A 3rodA-3ddmA:
undetectable		 3rodA-3ddmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 8 ASP A 281
GLY A 315
GLU A 258
ARG A  38
 None
 0.92A 3s3mA-3ddmA:
undetectable		 3s3mA-3ddmA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 7 ARG A  71
THR A  75
VAL A  76
LEU A  77
 None
 1.02A 3uniA-3ddmA:
undetectable		 3uniA-3ddmA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 7 PRO A 233
ALA A 215
ALA A 249
ARG A 216
 None
 0.80A 3ur0B-3ddmA:
undetectable		 3ur0B-3ddmA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 GLN A 134
ALA A 138
LEU A 136
ALA A 128
ALA A 132
 None
 1.13A 3ut5D-3ddmA:
undetectable		 3ut5D-3ddmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 6 GLU A  56
TYR A 309
HIS A 308
VAL A 149
 None
 1.19A 4a97E-3ddmA:
undetectable		 4a97E-3ddmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 5 HIS A 308
LEU A 176
LEU A 227
ASP A 185
 None
 1.21A 4aqlA-3ddmA:
6.4		 4aqlA-3ddmA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 11 ALA A 339
GLY A 153
GLY A 311
ASN A  60
ASN A 340
 None
 1.17A 4e47C-3ddmA:
undetectable		 4e47C-3ddmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		4 / 7 GLU A 242
LEU A 246
LEU A 254
LEU A 230
 None
 0.80A 4wg0B-3ddmA:
undetectable
4wg0C-3ddmA:
undetectable		 4wg0B-3ddmA:
3.24
4wg0C-3ddmA:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 8 LEU A 222
ASP A 185
ASN A 188
ALA A 189
VAL A 192
 None
 0.80A 4zbqA-3ddmA:
undetectable		 4zbqA-3ddmA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 9 LEU A 222
ASP A 185
ASN A 188
ALA A 189
VAL A 192
 None
 0.83A 4zbrA-3ddmA:
1.3		 4zbrA-3ddmA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_DIFA601_1
(SERUM ALBUMIN)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 9 LEU A 222
ASP A 185
ASN A 188
ALA A 189
VAL A 192
 None
 0.74A 5dbyA-3ddmA:
1.1		 5dbyA-3ddmA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 10 VAL A 370
GLY A 369
GLY A 367
LEU A  42
ILE A 122
 None
 0.99A 5vm8B-3ddmA:
undetectable		 5vm8B-3ddmA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		6 / 12 LEU A 282
PRO A 280
GLY A 286
GLY A 262
GLY A 290
GLY A 287
 None
 1.44A 5zhmB-3ddmA:
undetectable		 5zhmB-3ddmA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 12 LEU A 374
VAL A  45
VAL A  73
LEU A 344
ALA A  40
 None
 1.11A 6djzC-3ddmA:
undetectable		 6djzC-3ddmA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 3ddm PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
(Bordetella
bronchiseptica) 		5 / 11 ASP A 121
LEU A 322
GLY A 369
PRO A  89
LEU A 292
 None
 1.34A 6euqA-3ddmA:
undetectable		 6euqA-3ddmA:
24.66