SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ddy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_D_BRLD503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	4 / 4	ILE A 63 LEU A 83 VAL A 81 ILE A 12	RBF A 187 ( 4.6A) None None None	0.89A	1fm6D-3ddyA: undetectable	1fm6D-3ddyA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	4 / 8	LEU A 145 VAL A 6 VAL A 178 VAL A 120	None	1.02A	2bdmA-3ddyA: undetectable	2bdmA-3ddyA: 16.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	6 / 12	CYH A 47 ASP A 64 GLN A 65 ALA A 66 ASN A 101 ILE A 102	RBF A 187 (-3.3A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) RBF A 187 (-3.7A) RBF A 187 (-4.4A)	0.87A	3a35A-3ddyA: 29.7	3a35A-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	10 / 12	VAL A 41 CYH A 47 SER A 48 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ILE A 102	RBF A 187 ( 4.5A) RBF A 187 (-3.3A) RBF A 187 (-4.3A) RBF A 187 (-4.4A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) RBF A 187 (-3.2A) None RBF A 187 (-4.4A)	0.36A	3a35A-3ddyA: 29.7	3a35A-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	6 / 12	CYH A 47 ASP A 64 GLN A 65 ALA A 66 ASN A 101 ILE A 102	RBF A 187 (-3.3A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) RBF A 187 (-3.7A) RBF A 187 (-4.4A)	0.79A	3a35B-3ddyA: 30.7	3a35B-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	10 / 12	VAL A 41 CYH A 47 SER A 48 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ILE A 102	RBF A 187 ( 4.5A) RBF A 187 (-3.3A) RBF A 187 (-4.3A) RBF A 187 (-4.4A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) RBF A 187 (-3.2A) None RBF A 187 (-4.4A)	0.33A	3a35B-3ddyA: 30.7	3a35B-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	7 / 12	CYH A 47 ASP A 64 GLN A 65 ALA A 66 THR A 70 ASN A 101 ILE A 102	RBF A 187 (-3.3A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) None RBF A 187 (-3.7A) RBF A 187 (-4.4A)	0.80A	3a3bA-3ddyA: 29.3	3a3bA-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	10 / 12	VAL A 41 CYH A 47 SER A 48 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ILE A 102	RBF A 187 ( 4.5A) RBF A 187 (-3.3A) RBF A 187 (-4.3A) RBF A 187 (-4.4A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) RBF A 187 (-3.2A) None RBF A 187 (-4.4A)	0.37A	3a3bA-3ddyA: 29.3	3a3bA-3ddyA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	3ddy	LUMAZINE PROTEIN (Photobacterium leiognathi)	8 / 12	VAL A 41 SER A 48 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 70 ILE A 102	RBF A 187 ( 4.5A) RBF A 187 (-4.3A) RBF A 187 (-4.4A) RBF A 187 (-4.4A) RBF A 187 (-3.7A) RBF A 187 (-3.1A) None RBF A 187 (-4.4A)	1.48A	3a3bA-3ddyA: 29.3	3a3bA-3ddyA: 55.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_D_BRLD503_2","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",4,"ILE A  63;LEU A  83;VAL A  81;ILE A  12","RBF A 187 ( 4.6A);None;None;None","0.89A","1fm6D-3ddyA:undetectable","1fm6D-3ddyA:19.93"],["2BDM_A_TMIA503_1","CYTOCHROME P450 2B4","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",4,"LEU A 145;VAL A   6;VAL A 178;VAL A 120","None","1.02A","2bdmA-3ddyA:undetectable","2bdmA-3ddyA:16.70"],["3A35_A_RBFA191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",6,"CYH A  47;ASP A  64;GLN A  65;ALA A  66;ASN A 101;ILE A 102","RBF A 187 (-3.3A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);RBF A 187 (-3.7A);RBF A 187 (-4.4A)","0.87A","3a35A-3ddyA:29.7","3a35A-3ddyA:55.56"],["3A35_A_RBFA191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",10,"VAL A  41;CYH A  47;SER A  48;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ILE A 102","RBF A 187 ( 4.5A);RBF A 187 (-3.3A);RBF A 187 (-4.3A);RBF A 187 (-4.4A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);RBF A 187 (-3.2A);None;RBF A 187 (-4.4A)","0.36A","3a35A-3ddyA:29.7","3a35A-3ddyA:55.56"],["3A35_B_RBFB191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",6,"CYH A  47;ASP A  64;GLN A  65;ALA A  66;ASN A 101;ILE A 102","RBF A 187 (-3.3A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);RBF A 187 (-3.7A);RBF A 187 (-4.4A)","0.79A","3a35B-3ddyA:30.7","3a35B-3ddyA:55.56"],["3A35_B_RBFB191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",10,"VAL A  41;CYH A  47;SER A  48;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ILE A 102","RBF A 187 ( 4.5A);RBF A 187 (-3.3A);RBF A 187 (-4.3A);RBF A 187 (-4.4A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);RBF A 187 (-3.2A);None;RBF A 187 (-4.4A)","0.33A","3a35B-3ddyA:30.7","3a35B-3ddyA:55.56"],["3A3B_A_RBFA191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",7,"CYH A  47;ASP A  64;GLN A  65;ALA A  66;THR A  70;ASN A 101;ILE A 102","RBF A 187 (-3.3A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);None;RBF A 187 (-3.7A);RBF A 187 (-4.4A)","0.80A","3a3bA-3ddyA:29.3","3a3bA-3ddyA:55.56"],["3A3B_A_RBFA191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",10,"VAL A  41;CYH A  47;SER A  48;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ILE A 102","RBF A 187 ( 4.5A);RBF A 187 (-3.3A);RBF A 187 (-4.3A);RBF A 187 (-4.4A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);RBF A 187 (-3.2A);None;RBF A 187 (-4.4A)","0.37A","3a3bA-3ddyA:29.3","3a3bA-3ddyA:55.56"],["3A3B_A_RBFA191_1","LUMAZINE PROTEIN","3ddy","LUMAZINE PROTEIN","Photobacterium leiognathi",8,"VAL A  41;SER A  48;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  70;ILE A 102","RBF A 187 ( 4.5A);RBF A 187 (-4.3A);RBF A 187 (-4.4A);RBF A 187 (-4.4A);RBF A 187 (-3.7A);RBF A 187 (-3.1A);None;RBF A 187 (-4.4A)","1.48A","3a3bA-3ddyA:29.3","3a3bA-3ddyA:55.56"]]