SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 770
ASP A 773
TYR A 874
ARG A 877
 None
 1.34A 1ceaA-3decA:
undetectable
1ceaB-3decA:
undetectable		 1ceaA-3decA:
6.11
1ceaB-3decA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 770
ASP A 773
TYR A 874
ARG A 877
 None
 1.23A 1ceaB-3decA:
undetectable		 1ceaB-3decA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 VAL A 329
LEU A 272
VAL A 271
LEU A 233
 None
 0.89A 1cqpA-3decA:
2.0
1cqpB-3decA:
undetectable		 1cqpA-3decA:
11.64
1cqpB-3decA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  39
TYR A 215
PHE A  38
 None
 0.88A 1eqbB-3decA:
undetectable		 1eqbB-3decA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  39
TYR A 215
PHE A  38
 None
 0.86A 1eqbA-3decA:
undetectable		 1eqbA-3decA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  39
TYR A 215
PHE A  38
 None
 0.88A 1eqbD-3decA:
undetectable		 1eqbD-3decA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  39
TYR A 215
PHE A  38
 None
 0.86A 1eqbC-3decA:
undetectable		 1eqbC-3decA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 538
LEU A 982
GLY A 969
TYR A 981
GLY A 535
 None
 1.22A 1httB-3decA:
undetectable		 1httB-3decA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 234
HIS A 237
ASP A 296
 None
 0.86A 1i9gA-3decA:
2.4		 1i9gA-3decA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.29A 1kifA-3decA:
undetectable		 1kifA-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.29A 1kifB-3decA:
undetectable		 1kifB-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.29A 1kifC-3decA:
undetectable		 1kifC-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.28A 1kifD-3decA:
undetectable		 1kifD-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.28A 1kifE-3decA:
undetectable		 1kifE-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.29A 1kifF-3decA:
undetectable		 1kifF-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.28A 1kifG-3decA:
undetectable		 1kifG-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.28A 1kifH-3decA:
undetectable		 1kifH-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 383
PHE A 636
VAL A 348
 None
 0.86A 1kijA-3decA:
undetectable		 1kijA-3decA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 947
ASP A 578
TYR A  95
TRP A 205
 None
 0.94A 1v7zC-3decA:
undetectable		 1v7zC-3decA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 947
ASP A 578
TYR A  95
TRP A 205
 None
 0.96A 1v7zD-3decA:
undetectable		 1v7zD-3decA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 947
ASP A 578
TYR A  95
TRP A 205
 None
 0.95A 1v7zE-3decA:
undetectable		 1v7zE-3decA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 947
ASP A 578
TYR A  95
TRP A 205
 None
 0.96A 1v7zF-3decA:
undetectable		 1v7zF-3decA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.23A 1ve9A-3decA:
undetectable		 1ve9A-3decA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.40A 1xidA-3decA:
3.7		 1xidA-3decA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.37A 2du8G-3decA:
undetectable		 2du8G-3decA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 539
TYR A 525
ILE A 554
GLY A 535
 None
 1.34A 2du8J-3decA:
undetectable		 2du8J-3decA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_D_RBFD228_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 TYR A  27
PRO A  26
TYR A 215
PHE A  38
TYR A 217
 None
 1.44A 2fl5C-3decA:
5.7
2fl5D-3decA:
3.5		 2fl5C-3decA:
11.71
2fl5D-3decA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 307
GLY A 330
VAL A 452
LEU A 245
PHE A 243
 None
 1.16A 2oz7A-3decA:
undetectable		 2oz7A-3decA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  94
ARG A 206
TYR A  95
ASP A 203
 None
 1.00A 2qebA-3decA:
undetectable		 2qebA-3decA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  94
ARG A 206
TYR A  95
ASP A 203
 None
 1.01A 2qebB-3decA:
undetectable		 2qebB-3decA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 935
LEU A 942
TYR A 874
GLU A 872
 None
 0.97A 2vq5B-3decA:
undetectable		 2vq5B-3decA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.39A 2xinB-3decA:
11.0		 2xinB-3decA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.39A 2xinD-3decA:
3.8		 2xinD-3decA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 MET A 500
GLU A 410
ASN A 412
 None
 0.76A 3a27A-3decA:
2.0		 3a27A-3decA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 876
LEU A 978
GLY A 976
TYR A 539
 None
 0.90A 3af0A-3decA:
undetectable		 3af0A-3decA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 469
ASN A 466
HIS A 435
ALA A 434
 None
 1.07A 3frqA-3decA:
undetectable		 3frqA-3decA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 469
ASN A 466
HIS A 435
ALA A 434
 None
 1.07A 3frqB-3decA:
undetectable		 3frqB-3decA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 428
LEU A 425
GLN A 165
 None
 0.77A 3g4lA-3decA:
undetectable		 3g4lA-3decA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A303_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ASN A 412
SER A 150
SER A 208
ARG A 192
 None
 1.36A 3hlwA-3decA:
0.0		 3hlwA-3decA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASN A 412
SER A 150
SER A 208
ARG A 192
 None
 1.37A 3hlwB-3decA:
undetectable		 3hlwB-3decA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 460
GLU A 414
TRP A 555
 None
 0.84A 3hrdA-3decA:
undetectable
3hrdE-3decA:
undetectable
3hrdF-3decA:
undetectable		 3hrdA-3decA:
18.47
3hrdE-3decA:
18.47
3hrdF-3decA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 406
GLU A 303
SER A 334
ILE A 454
 None
 1.06A 3jz0B-3decA:
undetectable		 3jz0B-3decA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_D_AG2D1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 ASP A 770
GLY A 530
ARG A 877
ASP A 876
TYR A 874
 None
 1.46A 3n2oC-3decA:
6.9
3n2oD-3decA:
4.4		 3n2oC-3decA:
21.90
3n2oD-3decA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 HIS A 895
LEU A 606
TRP A 557
ALA A 528
LEU A 526
 None
 1.24A 3n8xA-3decA:
undetectable		 3n8xA-3decA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 310
GLY A 330
VAL A 271
GLY A 241
ILE A 242
 None
 1.10A 3nu9B-3decA:
undetectable		 3nu9B-3decA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 310
VAL A 271
GLY A 241
ILE A 242
LEU A 263
 None
 1.20A 3ogpB-3decA:
undetectable		 3ogpB-3decA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 175
ASN A 157
LEU A 161
ASP A 174
 None
 1.10A 3oi8A-3decA:
undetectable		 3oi8A-3decA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 889
GLY A 861
PRO A 890
PRO A 936
ASP A 858
 None
 1.43A 3t8nD-3decA:
undetectable
3t8nF-3decA:
undetectable		 3t8nD-3decA:
7.63
3t8nF-3decA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 634
LEU A 639
PRO A 667
SER A 637
 None
 1.02A 3vlnA-3decA:
undetectable		 3vlnA-3decA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.41A 3ximB-3decA:
2.2		 3ximB-3decA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.39A 3ximD-3decA:
3.6		 3ximD-3decA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 335
TYR A 238
HIS A 237
VAL A 297
 None
 0.94A 4a97A-3decA:
1.7		 4a97A-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 460
GLU A 524
TYR A 501
VAL A 506
 None
 1.10A 4a97A-3decA:
1.7		 4a97A-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 335
TYR A 238
HIS A 237
VAL A 297
 None
 0.95A 4a97D-3decA:
1.6		 4a97D-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A 335
TYR A 238
HIS A 237
VAL A 297
 None
 0.98A 4a97E-3decA:
1.6		 4a97E-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 335
TYR A 238
HIS A 237
VAL A 297
 None
 0.99A 4a97H-3decA:
1.0		 4a97H-3decA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  39
TYR A  44
SER A  46
 None
 0.82A 4at0A-3decA:
undetectable		 4at0A-3decA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.38A 4b7nA-3decA:
undetectable		 4b7nA-3decA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.32A 4cpzC-3decA:
undetectable		 4cpzC-3decA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.30A 4cpzE-3decA:
undetectable		 4cpzE-3decA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.35A 4cpzF-3decA:
undetectable		 4cpzF-3decA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.37A 4cpzG-3decA:
undetectable		 4cpzG-3decA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 192
ARG A 206
TRP A 193
 None
 1.36A 4cpzH-3decA:
undetectable		 4cpzH-3decA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY A 817
ILE A 808
TRP A 843
VAL A 844
 None
 1.27A 4d33B-3decA:
undetectable		 4d33B-3decA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A 109
VAL A  96
ILE A  94
 None
 0.58A 4emaA-3decA:
undetectable		 4emaA-3decA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 874
ARG A 877
THR A 903
GLY A 530
 None
 0.95A 4eq4A-3decA:
2.3		 4eq4A-3decA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 874
ARG A 877
THR A 903
GLY A 530
 None
 0.95A 4eqlB-3decA:
2.2		 4eqlB-3decA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 211
ASN A 164
GLY A 166
SER A 167
 None
 0.96A 4f93B-3decA:
8.1		 4f93B-3decA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 485
ARG A 386
HIS A 389
 None
 1.08A 4fubA-3decA:
undetectable		 4fubA-3decA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A  68
PRO A  69
SER A  70
 None
 0.18A 4k50I-3decA:
undetectable		 4k50I-3decA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.91A 4k8cA-3decA:
undetectable		 4k8cA-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.91A 4kahA-3decA:
undetectable		 4kahA-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.92A 4kahB-3decA:
undetectable		 4kahB-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.90A 4kanA-3decA:
undetectable		 4kanA-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.92A 4kanB-3decA:
undetectable		 4kanB-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.93A 4kbeA-3decA:
undetectable		 4kbeA-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.95A 4kbeB-3decA:
undetectable		 4kbeB-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 874
ARG A 877
THR A 903
GLY A 530
 None
 0.89A 4l39B-3decA:
3.0		 4l39B-3decA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.92A 4lbgA-3decA:
undetectable		 4lbgA-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 456
TYR A 485
PRO A 391
 None
 0.90A 4lbgB-3decA:
undetectable		 4lbgB-3decA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 445
ASP A 409
ARG A 212
 None
 0.85A 4mx0A-3decA:
undetectable		 4mx0A-3decA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  27
THR A 325
HIS A  21
TYR A 215
 None
 1.46A 4oltB-3decA:
undetectable		 4oltB-3decA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  61
ASN A 108
PHE A 107
 None
 0.79A 4pd9A-3decA:
undetectable		 4pd9A-3decA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A  27
THR A 325
HIS A  21
TYR A 215
 None
 1.44A 4qwpA-3decA:
undetectable		 4qwpA-3decA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 501
PRO A 975
LEU A 522
TYR A 539
 None
 1.34A 4w5qA-3decA:
3.3		 4w5qA-3decA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 932
LEU A 961
THR A 888
VAL A 912
 None
 0.99A 4wnvD-3decA:
undetectable		 4wnvD-3decA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.43A 4xiaB-3decA:
4.3		 4xiaB-3decA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 501
PRO A 975
LEU A 522
TYR A 539
 None
 1.22A 4z4cA-3decA:
undetectable		 4z4cA-3decA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 611
ARG A 868
PHE A 713
ASP A 711
 None
 1.15A 5a06A-3decA:
undetectable		 5a06A-3decA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 611
ARG A 868
PHE A 713
ASP A 711
 None
 1.15A 5a06B-3decA:
undetectable		 5a06B-3decA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 611
ARG A 868
PHE A 713
ASP A 711
 None
 1.16A 5a06C-3decA:
undetectable		 5a06C-3decA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 611
ARG A 868
PHE A 713
ASP A 711
 None
 1.16A 5a06D-3decA:
undetectable		 5a06D-3decA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 611
ARG A 868
PHE A 713
ASP A 711
 None
 1.15A 5a06F-3decA:
undetectable		 5a06F-3decA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 753
PHE A 854
ILE A 994
 None
 0.74A 5dzk1-3decA:
undetectable
5dzkF-3decA:
2.8
5dzkM-3decA:
1.6		 5dzk1-3decA:
13.33
5dzkF-3decA:
12.87
5dzkM-3decA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.14A 5eeuF-3decA:
0.0
5eeuG-3decA:
0.0		 5eeuF-3decA:
5.71
5eeuG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.14A 5eevF-3decA:
0.0
5eevG-3decA:
0.0		 5eevF-3decA:
5.71
5eevG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.14A 5eewF-3decA:
0.0
5eewG-3decA:
0.0		 5eewF-3decA:
5.71
5eewG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.14A 5eexF-3decA:
0.0
5eexG-3decA:
0.0		 5eexF-3decA:
5.71
5eexG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.13A 5eeyF-3decA:
0.0
5eeyG-3decA:
0.0		 5eeyF-3decA:
5.71
5eeyG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.13A 5eezF-3decA:
0.0
5eezG-3decA:
0.0		 5eezF-3decA:
5.71
5eezG-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.13A 5ef0F-3decA:
0.0
5ef0G-3decA:
0.0		 5ef0F-3decA:
5.71
5ef0G-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.14A 5ef1F-3decA:
0.0
5ef1G-3decA:
0.0		 5ef1F-3decA:
5.71
5ef1G-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.13A 5ef2F-3decA:
0.0
5ef2G-3decA:
0.0		 5ef2F-3decA:
5.71
5ef2G-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 424
ALA A 426
GLY A 458
HIS A 416
ILE A 413
 None
 1.13A 5ef3F-3decA:
0.0
5ef3G-3decA:
0.0		 5ef3F-3decA:
5.71
5ef3G-3decA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 945
ASP A 770
PRO A 765
THR A 972
TYR A 897
 K  A1101 (-4.9A)
None
None
None
None
 1.35A 5hfjG-3decA:
undetectable		 5hfjG-3decA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 339
TYR A 517
GLU A 486
SER A 456
ILE A 454
 None
 1.22A 5igwA-3decA:
undetectable		 5igwA-3decA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PRO A 585
GLY A 580
PHE A 107
ARG A 192
 None
 1.16A 5jcnB-3decA:
undetectable		 5jcnB-3decA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 HIS A 895
VAL A 609
LEU A 606
TRP A 557
ALA A 528
LEU A 526
 None
 1.38A 5kirA-3decA:
undetectable		 5kirA-3decA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A 101
LEU A 207
ARG A 192
ARG A 206
 None
 1.04A 5l6eA-3decA:
undetectable
5l6eB-3decA:
undetectable		 5l6eA-3decA:
12.95
5l6eB-3decA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 169
PRO A 391
ASP A 409
 None
 0.82A 5l8dB-3decA:
undetectable		 5l8dB-3decA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 169
PRO A 391
ASP A 409
 None
 0.82A 5mwuB-3decA:
undetectable		 5mwuB-3decA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 357
HIS A 358
VAL A 365
 None
 0.91A 5trqB-3decA:
undetectable		 5trqB-3decA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 976
ARG A 764
GLN A 901
ASP A 770
 None
 1.07A 5vlmA-3decA:
undetectable		 5vlmA-3decA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A  95
GLU A  86
GLY A 576
GLY A 588
 None
 0.97A 5x7pB-3decA:
6.8		 5x7pB-3decA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.44A 5ximA-3decA:
5.7		 5ximA-3decA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TRP A 555
HIS A 356
GLU A 414
GLU A 460
HIS A 416
 None
 1.39A 5ximC-3decA:
10.6		 5ximC-3decA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 601
TRP A 571
HIS A 603
 None
 0.94A 5xipA-3decA:
undetectable		 5xipA-3decA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 601
TRP A 571
HIS A 895
 None
 1.06A 5xipA-3decA:
undetectable		 5xipA-3decA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A  22
THR A 325
LEU A 272
ASN A 448
PHE A 243
 None
 1.21A 5ybbB-3decA:
undetectable		 5ybbB-3decA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 389
HIS A 416
TRP A 555
ARG A 206
 None
 1.10A 6b94A-3decA:
undetectable		 6b94A-3decA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ILE A 899
ASN A 593
CYH A 533
 None
 0.85A 6bp4A-3decA:
undetectable		 6bp4A-3decA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ALA A 804
THR A 803
ILE A 760
VAL A 806
 None
 0.92A 6cduF-3decA:
2.0
6cduJ-3decA:
1.7		 6cduF-3decA:
15.78
6cduJ-3decA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 455
ILE A 408
ASP A 409
 None
 0.67A 6i0y7-3decA:
undetectable		 6i0y7-3decA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 668
GLU A 666
ASP A 638
GLU A 641
 None
 1.40A 6mn4F-3decA:
undetectable		 6mn4F-3decA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dec BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 161
TRP A 136
ASP A 177
THR A 176
 None
 1.16A 6nknC-3decA:
undetectable
6nknN-3decA:
undetectable
6nknP-3decA:
undetectable		 6nknC-3decA:
12.09
6nknN-3decA:
18.53
6nknP-3decA:
12.09