SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3dee PUTATIVE REGULATORY
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 226
ILE A 225
MET A 184
LEU A 159
ILE A 140
 None
 1.01A 1bsxA-3deeA:
undetectable		 1bsxA-3deeA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3dee PUTATIVE REGULATORY
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 226
ILE A 225
MET A 184
LEU A 159
ILE A 140
 None
 1.02A 1bsxB-3deeA:
undetectable		 1bsxB-3deeA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3dee PUTATIVE REGULATORY
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 ILE A 226
ILE A 118
ARG A 223
LEU A 229
 None
 1.24A 5dzkh-3deeA:
undetectable
5dzkn-3deeA:
undetectable
5dzkv-3deeA:
undetectable		 5dzkh-3deeA:
22.05
5dzkn-3deeA:
22.05
5dzkv-3deeA:
1.25