SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3del'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 7 ALA B 201
LEU B 202
VAL B 177
MET B 178
 None
 0.70A 1hk2A-3delB:
undetectable		 1hk2A-3delB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 8 GLY B 221
VAL B  97
GLU B  48
ILE B 111
 None
 0.67A 1pk7B-3delB:
undetectable		 1pk7B-3delB:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		5 / 11 PHE B  47
HIS B 264
THR B  43
ALA B  42
ASN B  41
 None
 1.46A 2gl0B-3delB:
undetectable
2gl0C-3delB:
undetectable		 2gl0B-3delB:
24.50
2gl0C-3delB:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		5 / 9 ILE B  98
ALA B  96
GLU B 239
GLY B  72
LEU B  71
 None
 1.14A 2v0mB-3delB:
undetectable		 2v0mB-3delB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 6 ALA B  64
ILE B  61
LEU B  75
ALA B  96
 None
 0.79A 3r9sA-3delB:
undetectable		 3r9sA-3delB:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 6 ALA B  64
ILE B  61
LEU B  75
ALA B  96
 None
 0.77A 3r9sC-3delB:
undetectable		 3r9sC-3delB:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 6 VAL B 186
LEU B 126
ILE B 207
VAL B 162
 None
 0.95A 4a9kA-3delB:
undetectable		 4a9kA-3delB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 5 VAL B 186
LEU B 126
ILE B 207
VAL B 162
 None
 0.79A 4a9kB-3delB:
undetectable		 4a9kB-3delB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		5 / 12 LEU B  71
PHE B  36
ALA B  64
GLU B 239
ALA B 236
 None
 1.25A 4fiaA-3delB:
undetectable		 4fiaA-3delB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		5 / 12 LEU B  71
PHE B  36
ALA B  64
GLU B 239
ALA B 236
 None
 1.25A 4fiaA-3delB:
undetectable		 4fiaA-3delB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		5 / 10 TYR B 116
ASP B  60
ILE B 240
LEU B 249
ILE B  94
 None
 1.32A 5hw8C-3delB:
undetectable
5hw8H-3delB:
undetectable		 5hw8C-3delB:
22.13
5hw8H-3delB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3del ARGININE BINDING
PROTEIN
(Chlamydia
trachomatis) 		4 / 6 GLU B  79
ALA B  64
LEU B  63
TYR B  44
 None
 1.04A 5igiA-3delB:
undetectable		 5igiA-3delB:
22.98