SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3deo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 SER A  92
MET A 100
ASP A 123
 None
 0.89A 4mm4B-3deoA:
undetectable		 4mm4B-3deoA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ASP A 224
GLY A 193
ASP A 190
 None
 0.68A 4xdtA-3deoA:
undetectable		 4xdtA-3deoA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 THR A  94
HIS A 199
LEU A 165
 None
 0.87A 5axdC-3deoA:
undetectable		 5axdC-3deoA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN
(Arabidopsis
thaliana) 		5 / 9 LEU A 179
ASP A 173
LEU A 164
LEU A 186
ALA A 197
 None
 1.00A 5dqfA-3deoA:
undetectable		 5dqfA-3deoA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 3deo SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 VAL A 115
GLU A 101
ILE A 120
 None
 0.58A 6f7lB-3deoA:
undetectable		 6f7lB-3deoA:
18.43