SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3df7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 GLN A 123
PRO A 125
GLU A 163
ASP A 238
 None
 1.22A 1dtlA-3df7A:
undetectable		 1dtlA-3df7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A 105
PHE A   9
PHE A   7
GLY A  99
 None
 1.08A 3em0B-3df7A:
undetectable		 3em0B-3df7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 198
VAL A 281
LEU A 299
THR A 251
 None
 0.83A 3roxA-3df7A:
3.3		 3roxA-3df7A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 281
GLY A 197
LYS A 283
 None
 0.78A 4k50A-3df7A:
undetectable		 4k50A-3df7A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 281
GLY A 197
LYS A 283
 None
 0.77A 4k50E-3df7A:
undetectable		 4k50E-3df7A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 LEU A  98
ASN A  97
LEU A 249
ILE A 105
 None
 1.01A 4okxA-3df7A:
undetectable		 4okxA-3df7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 167
ILE A 204
SER A 205
ASP A 238
PRO A 240
 None
 1.27A 4rtpA-3df7A:
undetectable		 4rtpA-3df7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_D_ACTD401_0
(PROTON-GATED ION
CHANNEL)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 PHE A  49
ARG A  46
ARG A  15
ILE A  16
 None
 1.30A 4zzcD-3df7A:
0.0
4zzcE-3df7A:
0.0		 4zzcD-3df7A:
20.71
4zzcE-3df7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 110
LEU A 132
ARG A 130
PRO A 140
GLY A 158
 None
 1.29A 5ogcB-3df7A:
undetectable		 5ogcB-3df7A:
18.94