SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dfa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.09A 1nsiA-3dfaA:
undetectable
1nsiB-3dfaA:
undetectable		 1nsiA-3dfaA:
21.17
1nsiB-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.08A 1nsiA-3dfaA:
undetectable
1nsiB-3dfaA:
undetectable		 1nsiA-3dfaA:
21.17
1nsiB-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.07A 1nsiC-3dfaA:
undetectable
1nsiD-3dfaA:
undetectable		 1nsiC-3dfaA:
21.17
1nsiD-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.08A 1nsiC-3dfaA:
undetectable
1nsiD-3dfaA:
undetectable		 1nsiC-3dfaA:
21.17
1nsiD-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 10 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 0.98A 1pxxA-3dfaA:
undetectable		 1pxxA-3dfaA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 0.98A 1pxxC-3dfaA:
undetectable		 1pxxC-3dfaA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 5 ILE A 240
TRP A 229
LEU A 244
PRO A 204
 None
 1.20A 1s8fA-3dfaA:
undetectable
1s8fB-3dfaA:
undetectable		 1s8fA-3dfaA:
25.61
1s8fB-3dfaA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 PHE A 157
THR A  48
LEU A  52
ILE A  38
 None
 0.83A 1t87B-3dfaA:
undetectable		 1t87B-3dfaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.10A 2nsiA-3dfaA:
undetectable
2nsiB-3dfaA:
undetectable		 2nsiA-3dfaA:
21.17
2nsiB-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.09A 2nsiA-3dfaA:
undetectable
2nsiB-3dfaA:
undetectable		 2nsiA-3dfaA:
21.17
2nsiB-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.09A 2nsiC-3dfaA:
undetectable
2nsiD-3dfaA:
undetectable		 2nsiC-3dfaA:
21.17
2nsiD-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.09A 2nsiC-3dfaA:
undetectable
2nsiD-3dfaA:
undetectable		 2nsiC-3dfaA:
21.17
2nsiD-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 8 ASP A 129
SER A 154
TYR A 182
CYH A 186
 None
 1.14A 2xz5A-3dfaA:
undetectable
2xz5C-3dfaA:
undetectable		 2xz5A-3dfaA:
20.81
2xz5C-3dfaA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 11 CYH A 257
LEU A 258
LEU A 239
ALA A 191
VAL A 188
 None
 1.18A 3e22D-3dfaA:
undetectable		 3e22D-3dfaA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.07A 3e7gA-3dfaA:
undetectable
3e7gB-3dfaA:
undetectable		 3e7gA-3dfaA:
21.33
3e7gB-3dfaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.07A 3e7gA-3dfaA:
undetectable
3e7gB-3dfaA:
undetectable		 3e7gA-3dfaA:
21.33
3e7gB-3dfaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.08A 3e7gC-3dfaA:
undetectable
3e7gD-3dfaA:
undetectable		 3e7gC-3dfaA:
21.33
3e7gD-3dfaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 8 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.08A 3e7gC-3dfaA:
undetectable
3e7gD-3dfaA:
undetectable		 3e7gC-3dfaA:
21.33
3e7gD-3dfaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_A_H4BA1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.14A 3ej8A-3dfaA:
0.0
3ej8B-3dfaA:
0.0		 3ej8A-3dfaA:
21.56
3ej8B-3dfaA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.13A 3ej8A-3dfaA:
0.0
3ej8B-3dfaA:
0.0		 3ej8A-3dfaA:
21.56
3ej8B-3dfaA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_C_H4BC3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.09A 3ej8C-3dfaA:
0.0
3ej8D-3dfaA:
0.0		 3ej8C-3dfaA:
21.56
3ej8D-3dfaA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_D_H4BD4902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.10A 3ej8C-3dfaA:
0.0
3ej8D-3dfaA:
0.0		 3ej8C-3dfaA:
21.56
3ej8D-3dfaA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		3 / 3 GLY A 220
PRO A 204
LEU A 244
 None
 0.55A 3hcpB-3dfaA:
undetectable		 3hcpB-3dfaA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.07A 4coxA-3dfaA:
undetectable		 4coxA-3dfaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.08A 4coxB-3dfaA:
undetectable		 4coxB-3dfaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.07A 4coxD-3dfaA:
undetectable		 4coxD-3dfaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 8 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.12A 4cx7A-3dfaA:
undetectable
4cx7B-3dfaA:
undetectable		 4cx7A-3dfaA:
21.17
4cx7B-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 8 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.09A 4cx7A-3dfaA:
undetectable
4cx7B-3dfaA:
undetectable		 4cx7A-3dfaA:
21.17
4cx7B-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 8 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.07A 4cx7C-3dfaA:
undetectable
4cx7D-3dfaA:
undetectable		 4cx7C-3dfaA:
21.17
4cx7D-3dfaA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.08A 4cx7C-3dfaA:
undetectable
4cx7D-3dfaA:
undetectable		 4cx7C-3dfaA:
21.17
4cx7D-3dfaA:
21.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		8 / 12 GLY A  14
VAL A  21
ALA A  34
GLY A  89
GLU A  90
LEU A 136
ILE A 149
LEU A 153
 None
 0.80A 4ifgA-3dfaA:
34.6		 4ifgA-3dfaA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		8 / 12 GLY A  14
VAL A  21
ALA A  34
LEU A  69
GLY A  89
GLU A  90
LEU A 136
ILE A 149
 None
 0.72A 4ifgA-3dfaA:
34.6		 4ifgA-3dfaA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		8 / 12 GLY A  14
VAL A  21
LYS A  36
GLY A  89
GLU A  90
LEU A 136
ILE A 149
LEU A 153
 None
 1.17A 4ifgA-3dfaA:
34.6		 4ifgA-3dfaA:
42.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.11A 4nosA-3dfaA:
undetectable
4nosB-3dfaA:
undetectable		 4nosA-3dfaA:
20.41
4nosB-3dfaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ARG A 241
ILE A 232
TRP A 229
PHE A 224
 None
 1.11A 4nosC-3dfaA:
undetectable
4nosD-3dfaA:
undetectable		 4nosC-3dfaA:
20.41
4nosD-3dfaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 TRP A 229
PHE A 224
ARG A 241
ILE A 232
 None
 1.12A 4nosC-3dfaA:
undetectable
4nosD-3dfaA:
undetectable		 4nosC-3dfaA:
20.41
4nosD-3dfaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.11A 4otyA-3dfaA:
undetectable		 4otyA-3dfaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.08A 4rrwC-3dfaA:
undetectable		 4rrwC-3dfaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 LEU A 244
GLY A 192
ALA A 191
SER A 190
LEU A 130
 None
 1.08A 4rrzC-3dfaA:
undetectable		 4rrzC-3dfaA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		5 / 12 CYH A 257
LEU A 258
LEU A 239
ALA A 191
VAL A 188
 None
 1.01A 4x1yD-3dfaA:
undetectable		 4x1yD-3dfaA:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 6 ALA A  34
LYS A  36
LEU A  85
LEU A 136
 None
 0.84A 4xoyA-3dfaA:
8.2		 4xoyA-3dfaA:
32.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 ILE A  95
ILE A 110
PHE A 101
LEU A 130
 None
 0.83A 5fukA-3dfaA:
undetectable
5fukB-3dfaA:
undetectable		 5fukA-3dfaA:
19.53
5fukB-3dfaA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920
(Cryptosporidium
parvum) 		4 / 7 LEU A 244
PRO A 204
ILE A 197
LEU A 198
 None
 1.03A 5fxtA-3dfaA:
undetectable		 5fxtA-3dfaA:
22.49