SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dfh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 GLY A 368
GLY A  38
PHE A  37
GLY A 318
 None
 0.70A 1d0vA-3dfhA:
undetectable		 1d0vA-3dfhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 11 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.01A 1dhiB-3dfhA:
undetectable		 1dhiB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.03A 1dhjB-3dfhA:
undetectable		 1dhjB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.03A 1draB-3dfhA:
undetectable		 1draB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.02A 1drbB-3dfhA:
undetectable		 1drbB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.13A 1dyiB-3dfhA:
undetectable		 1dyiB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		3 / 3 GLN A 285
ILE A 367
HIS A 324
 None
 0.68A 1fm9A-3dfhA:
undetectable		 1fm9A-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 GLY A 368
GLY A  38
PHE A  37
GLY A 318
 None
 0.67A 1jhaA-3dfhA:
undetectable		 1jhaA-3dfhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		3 / 3 GLN A 285
ILE A 367
HIS A 324
 None
 0.69A 1k74A-3dfhA:
undetectable		 1k74A-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 7 ASN A 322
GLY A  94
PRO A 291
ALA A 292
 None
 0.75A 1n49A-3dfhA:
undetectable		 1n49A-3dfhA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 7 ASP A 101
GLY A 318
ALA A 292
ILE A 289
 None
 0.75A 1n49A-3dfhA:
undetectable		 1n49A-3dfhA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 7 TRP A 267
ILE A 286
LEU A 298
TRP A 308
 None
 1.47A 1q0yH-3dfhA:
undetectable
1q0yL-3dfhA:
undetectable		 1q0yH-3dfhA:
17.31
1q0yL-3dfhA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.05A 1qzfA-3dfhA:
undetectable		 1qzfA-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.06A 1qzfB-3dfhA:
undetectable		 1qzfB-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.06A 1qzfC-3dfhA:
undetectable		 1qzfC-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.06A 1qzfD-3dfhA:
undetectable		 1qzfD-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.06A 1qzfE-3dfhA:
undetectable		 1qzfE-3dfhA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.01A 1rx7A-3dfhA:
undetectable		 1rx7A-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 10 GLY A 318
ASP A 101
GLY A  94
PRO A 291
ALA A 292
 None
 1.04A 1sh9B-3dfhA:
undetectable		 1sh9B-3dfhA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 10 LEU A 212
ALA A 221
ILE A 247
HIS A 206
ASP A 207
 None
 1.46A 2b17A-3dfhA:
undetectable		 2b17A-3dfhA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		6 / 12 ILE A 276
LYS A 268
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.24A 2d0kA-3dfhA:
undetectable		 2d0kA-3dfhA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 6 LEU A 212
ALA A 221
HIS A 206
ASP A 207
 None
 1.34A 2dpzA-3dfhA:
undetectable		 2dpzA-3dfhA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 6 LEU A 359
ALA A 319
HIS A 337
TYR A 149
 None
 1.37A 2dpzA-3dfhA:
undetectable		 2dpzA-3dfhA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.02A 2drcB-3dfhA:
undetectable		 2drcB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 7 LEU A 270
LEU A 257
PHE A 261
PRO A 238
 None
 0.97A 2vq5B-3dfhA:
undetectable		 2vq5B-3dfhA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 9 ILE A 232
PHE A 191
VAL A 224
GLU A 223
 None
 0.87A 2vufA-3dfhA:
undetectable		 2vufA-3dfhA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 9 PHE A 220
ALA A 221
VAL A 224
GLU A 225
 None
 0.57A 2vufA-3dfhA:
undetectable		 2vufA-3dfhA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.03A 3drcB-3dfhA:
undetectable		 3drcB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 4 LEU A 260
GLY A 258
LEU A 257
GLU A 233
 None
 1.09A 3tgvB-3dfhA:
undetectable		 3tgvB-3dfhA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 11 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.08A 3tqbA-3dfhA:
undetectable		 3tqbA-3dfhA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 VAL A 141
ASP A 139
SER A 193
MET A 190
LEU A 156
 None
 1.48A 4a83A-3dfhA:
undetectable		 4a83A-3dfhA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 0.99A 4dfrB-3dfhA:
undetectable		 4dfrB-3dfhA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
LYS A 268
ILE A 286
LEU A 295
ILE A 279
 None
 1.06A 4dfrB-3dfhA:
undetectable		 4dfrB-3dfhA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 TYR A 183
ASP A 207
VAL A 224
LEU A 212
 None
 0.81A 4f8hA-3dfhA:
undetectable
4f8hB-3dfhA:
undetectable		 4f8hA-3dfhA:
21.67
4f8hB-3dfhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 TYR A 183
ASP A 207
VAL A 224
LEU A 212
 None
 0.79A 4f8hB-3dfhA:
undetectable
4f8hC-3dfhA:
undetectable		 4f8hB-3dfhA:
21.67
4f8hC-3dfhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 TYR A 183
ASP A 207
VAL A 224
LEU A 212
 None
 0.78A 4f8hC-3dfhA:
undetectable
4f8hD-3dfhA:
undetectable		 4f8hC-3dfhA:
21.67
4f8hD-3dfhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 TYR A 183
ASP A 207
VAL A 224
LEU A 212
 None
 0.79A 4f8hD-3dfhA:
undetectable
4f8hE-3dfhA:
undetectable		 4f8hD-3dfhA:
21.67
4f8hE-3dfhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 8 VAL A 224
LEU A 212
TYR A 183
ASP A 207
 None
 0.80A 4f8hA-3dfhA:
undetectable
4f8hE-3dfhA:
undetectable		 4f8hA-3dfhA:
21.67
4f8hE-3dfhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		3 / 3 ARG A 153
TYR A 358
ASN A 326
 None
 0.90A 4ffwB-3dfhA:
undetectable		 4ffwB-3dfhA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		3 / 3 ARG A 211
HIS A 209
TYR A 183
 None
 1.27A 4fu8A-3dfhA:
undetectable		 4fu8A-3dfhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		3 / 3 ARG A 211
HIS A 209
TYR A 183
 None
 1.36A 4fu9A-3dfhA:
undetectable		 4fu9A-3dfhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 0.97A 4kjlA-3dfhA:
undetectable		 4kjlA-3dfhA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 5 ILE A 276
LEU A 244
ASP A 234
VAL A 224
 None
 1.06A 4nkxB-3dfhA:
undetectable		 4nkxB-3dfhA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.01A 4pstA-3dfhA:
undetectable		 4pstA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.02A 4pthA-3dfhA:
undetectable		 4pthA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.00A 4pthA-3dfhA:
undetectable		 4pthA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.07A 4qleA-3dfhA:
undetectable		 4qleA-3dfhA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.04A 4x5fA-3dfhA:
undetectable		 4x5fA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.06A 4x5fB-3dfhA:
undetectable		 4x5fB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.07A 4x5gA-3dfhA:
undetectable		 4x5gA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		6 / 12 ILE A 276
LYS A 268
ILE A 286
LEU A 295
ILE A 279
THR A 241
 None
 1.15A 4x5gB-3dfhA:
undetectable		 4x5gB-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ILE A 276
LYS A 268
ILE A 286
LEU A 295
THR A 241
 None
 1.14A 4x5hA-3dfhA:
undetectable		 4x5hA-3dfhA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 5 GLY A 256
ARG A 280
GLY A 258
GLU A 259
 None
 1.08A 4z2eB-3dfhA:
undetectable
4z2eC-3dfhA:
undetectable		 4z2eB-3dfhA:
22.95
4z2eC-3dfhA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 7 GLU A 336
ARG A 280
GLU A 233
ASP A 234
 None
 1.03A 4zz8A-3dfhA:
undetectable		 4zz8A-3dfhA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 5 PRO A 237
HIS A 209
LEU A 188
PHE A 231
 None
 1.42A 5igjA-3dfhA:
undetectable		 5igjA-3dfhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		4 / 5 TYR A 138
MET A 134
THR A 133
LEU A 156
 None
 1.43A 5x1bW-3dfhA:
undetectable		 5x1bW-3dfhA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ASN A 262
ASN A 263
PHE A 261
ASP A 234
ILE A 276
 None
 1.32A 6dwnA-3dfhA:
undetectable		 6dwnA-3dfhA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 7 GLN A 285
GLY A  38
SER A  93
GLY A  94
VAL A  26
 None
 1.17A 6ekzA-3dfhA:
undetectable		 6ekzA-3dfhA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3dfh MANDELATE RACEMASE
(Vibrionales
bacterium
SWAT-3) 		5 / 12 ALA A  66
THR A 290
ILE A 289
LEU A 111
THR A   6
 None
 1.09A 7dfrA-3dfhA:
undetectable		 7dfrA-3dfhA:
18.88