SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.14A 1fohA-3dfuA:
undetectable		 1fohA-3dfuA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.14A 1fohB-3dfuA:
undetectable		 1fohB-3dfuA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.18A 1fohC-3dfuA:
undetectable		 1fohC-3dfuA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.19A 1fohD-3dfuA:
undetectable		 1fohD-3dfuA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 LEU A  60
VAL A  92
ILE A  79
GLY A  78
PRO A  84
 None
 1.01A 1k6cA-3dfuA:
undetectable		 1k6cA-3dfuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.13A 1pn0A-3dfuA:
undetectable		 1pn0A-3dfuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.13A 1pn0B-3dfuA:
undetectable		 1pn0B-3dfuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.19A 1pn0C-3dfuA:
undetectable		 1pn0C-3dfuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 10 GLY A  55
MET A  82
VAL A  57
ILE A  48
GLY A  52
 None
 1.18A 1pn0D-3dfuA:
undetectable		 1pn0D-3dfuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 12 LEU A  60
VAL A  92
ILE A  79
GLY A  78
PRO A  84
 None
 0.93A 2r5pA-3dfuA:
undetectable		 2r5pA-3dfuA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 12 LEU A  60
VAL A  92
ILE A  79
GLY A  78
PRO A  84
 None
 0.92A 2r5pC-3dfuA:
undetectable		 2r5pC-3dfuA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		5 / 12 LEU A  71
GLY A  89
ILE A  40
LEU A  45
ILE A  91
 None
 1.00A 3adxB-3dfuA:
undetectable		 3adxB-3dfuA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		4 / 8 SER A  88
GLY A  55
ILE A  48
ALA A  50
 None
 0.92A 3aodA-3dfuA:
undetectable		 3aodA-3dfuA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		4 / 7 VAL A  53
VAL A  57
LEU A  60
SER A  61
 None
 0.71A 3hs6B-3dfuA:
undetectable		 3hs6B-3dfuA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		3 / 3 ALA A  95
TRP A 103
VAL A 104
 None
 0.42A 4w9nC-3dfuA:
4.1		 4w9nC-3dfuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3dfu UNCHARACTERIZED
PROTEIN FROM
6-PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 SER A 170
ALA A 155
SER A 156
ALA A 177
 None
 0.93A 6bocA-3dfuA:
undetectable
6bocB-3dfuA:
undetectable
6bocC-3dfuA:
undetectable
6bocD-3dfuA:
undetectable		 6bocA-3dfuA:
8.25
6bocB-3dfuA:
8.25
6bocC-3dfuA:
8.25
6bocD-3dfuA:
8.25