SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		4 / 8 PHE A  95
ILE A  77
PRO A  91
LEU A  81
 None
 0.76A 1hmyA-3dh1A:
undetectable		 1hmyA-3dh1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		5 / 12 LEU A 100
ILE A 119
ALA A  72
VAL A  44
PHE A 152
 None
 1.28A 2qo4A-3dh1A:
undetectable		 2qo4A-3dh1A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		5 / 12 LEU A 100
ILE A 119
ALA A  72
VAL A  44
PHE A 152
 None
 1.29A 2qo6A-3dh1A:
undetectable		 2qo6A-3dh1A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		5 / 12 VAL A  80
VAL A  54
TYR A  50
GLY A  56
PHE A  95
 None
 1.21A 3mecA-3dh1A:
undetectable		 3mecA-3dh1A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		5 / 12 VAL A  80
VAL A  54
TYR A  50
GLY A  56
PHE A  95
 None
 1.24A 3medA-3dh1A:
undetectable
3medB-3dh1A:
undetectable		 3medA-3dh1A:
14.85
3medB-3dh1A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		5 / 11 LEU A 114
ALA A  76
GLY A  45
VAL A  44
VAL A 122
 None
 0.90A 3oxxD-3dh1A:
undetectable		 3oxxD-3dh1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		4 / 6 VAL A 104
SER A 136
ALA A 141
PHE A 152
 None
 1.09A 4nedA-3dh1A:
undetectable		 4nedA-3dh1A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens) 		3 / 3 MET A  30
MET A  48
TYR A 158
 None
 1.39A 4p6xI-3dh1A:
undetectable		 4p6xI-3dh1A:
20.78