SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  11
VAL A  34
LEU A  20
MET A 201
LEU A 108
 None
 1.35A 3h52D-3dhnA:
undetectable		 3h52D-3dhnA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.03A 3ln1A-3dhnA:
undetectable		 3ln1A-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.03A 3ln1B-3dhnA:
undetectable		 3ln1B-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.04A 3ln1C-3dhnA:
undetectable		 3ln1C-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.03A 3ln1D-3dhnA:
undetectable		 3ln1D-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.06A 3nt1A-3dhnA:
undetectable		 3nt1A-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.07A 3nt1B-3dhnA:
undetectable		 3nt1B-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 149
PHE A 148
PHE A 144
PHE A 107
 None
 1.04A 3wg7C-3dhnA:
undetectable
3wg7J-3dhnA:
undetectable		 3wg7C-3dhnA:
22.15
3wg7J-3dhnA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
VAL A  34
GLY A  11
ALA A  12
LEU A  21
 None
 1.18A 4rrwB-3dhnA:
undetectable		 4rrwB-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
VAL A  34
GLY A  11
ALA A  12
LEU A  21
 None
 1.18A 4rrzB-3dhnA:
undetectable		 4rrzB-3dhnA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 191
GLY A 188
ASN A 189
HIS A 222
 None
 1.39A 5a5zC-3dhnA:
undetectable		 5a5zC-3dhnA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.07A 5ikrB-3dhnA:
undetectable		 5ikrB-3dhnA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 1.09A 5jvzA-3dhnA:
undetectable		 5jvzA-3dhnA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  31
LEU A  25
VAL A  35
GLY A  11
ALA A  12
 None
 0.99A 5jw1A-3dhnA:
undetectable		 5jw1A-3dhnA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 135
ASP A 126
SER A 190
PRO A 162
GLY A 111
 None
 1.22A 5syeB-3dhnA:
6.1		 5syeB-3dhnA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3dhn NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E
(Bacteroides
thetaiotaomicron) 		4 / 6 VAL A   4
LEU A 205
LEU A 108
LEU A   9
 None
 0.99A 6f6sA-3dhnA:
undetectable
6f6sB-3dhnA:
undetectable		 6f6sA-3dhnA:
20.10
6f6sB-3dhnA:
16.34