SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dhx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZNC_A_BZ1A500_1 (CARBONIC ANHYDRASE IV)	3dhx	METHIONINE IMPORT ATP-BINDING PROTEIN METN (Escherichia coli)	5 / 10	HIS A 88 VAL A 90 PHE A 28 LEU A 38 THR A 41	None None None IOD A 263 ( 4.3A) None	1.48A	3zncA-3dhxA: undetectable	3zncA-3dhxA: 14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODI_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3dhx	METHIONINE IMPORT ATP-BINDING PROTEIN METN (Escherichia coli)	3 / 3	HIS A 88 GLU A 87 TRP A 84	None	0.98A	5odiD-3dhxA: undetectable	5odiD-3dhxA: 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODQ_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3dhx	METHIONINE IMPORT ATP-BINDING PROTEIN METN (Escherichia coli)	3 / 3	HIS A 88 GLU A 87 TRP A 84	None	0.89A	5odqD-3dhxA: undetectable	5odqD-3dhxA: 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODR_D_ACTD202_0 (METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D)	3dhx	METHIONINE IMPORT ATP-BINDING PROTEIN METN (Escherichia coli)	3 / 3	HIS A 88 GLU A 87 TRP A 84	None	0.99A	5odrD-3dhxA: undetectable	5odrD-3dhxA: 17.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ZNC_A_BZ1A500_1","CARBONIC ANHYDRASE IV","3dhx","METHIONINE IMPORT ATP-BINDING PROTEIN METN","Escherichia coli",5,"HIS A  88;VAL A  90;PHE A  28;LEU A  38;THR A  41","None;None;None;IOD A 263 ( 4.3A);None","1.48A","3zncA-3dhxA:undetectable","3zncA-3dhxA:14.61"],["5ODI_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3dhx","METHIONINE IMPORT ATP-BINDING PROTEIN METN","Escherichia coli",3,"HIS A  88;GLU A  87;TRP A  84","None","0.98A","5odiD-3dhxA:undetectable","5odiD-3dhxA:17.14"],["5ODQ_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3dhx","METHIONINE IMPORT ATP-BINDING PROTEIN METN","Escherichia coli",3,"HIS A  88;GLU A  87;TRP A  84","None","0.89A","5odqD-3dhxA:undetectable","5odqD-3dhxA:17.14"],["5ODR_D_ACTD202_0","METHYL-VIOLOGEN REDUCING HYDROGENASE, SUBUNIT D","3dhx","METHIONINE IMPORT ATP-BINDING PROTEIN METN","Escherichia coli",3,"HIS A  88;GLU A  87;TRP A  84","None","0.99A","5odrD-3dhxA:undetectable","5odrD-3dhxA:17.14"]]