SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 7 GLY A  29
HIS A  47
TYR A  51
PRO A  59
 None
 0.43A 1th6A-3dihA:
22.4		 1th6A-3dihA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 7 HIS A  47
TYR A  51
PRO A  59
LYS A  60
 None
 0.75A 1th6A-3dihA:
22.4		 1th6A-3dihA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 7 GLY A  29
HIS A  47
TYR A  51
PRO A  59
 None
 0.43A 2armA-3dihA:
22.4		 2armA-3dihA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 7 HIS A  47
TYR A  51
PRO A  59
LYS A  60
 None
 0.77A 2armA-3dihA:
22.4		 2armA-3dihA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		6 / 11 VAL A   2
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.66A 3bjwB-3dihA:
22.9		 3bjwB-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.81A 3bjwG-3dihA:
21.9		 3bjwG-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 10 VAL A   2
GLU A   4
GLY A   6
PRO A  17
LYS A  60
 None
 0.93A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 7 VAL A   2
GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 1.19A 3bjwC-3dihA:
22.1		 3bjwC-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		6 / 11 VAL A   2
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.70A 3bjwE-3dihA:
22.5		 3bjwE-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
 0.89A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		6 / 12 VAL A   2
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.67A 3bjwF-3dihA:
22.5		 3bjwF-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 8 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 1.07A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 8 LYS A  15
TYR A 103
ASN A 104
LYS A 106
 None
 1.20A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 8 LYS A  15
TYR A 103
LYS A 106
PHE A 113
 None
 1.43A 3bjwD-3dihA:
22.0		 3bjwD-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 8 VAL A   2
GLY A   6
LYS A   7
PRO A  17
LYS A  60
 None
 1.23A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 8 VAL A   2
GLY A   6
PRO A  17
LYS A  60
ARG A  63
 None
 1.00A 3bjwA-3dihA:
22.1		 3bjwA-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 11 VAL A   2
GLY A   6
LYS A  15
PRO A  17
SER A  20
 None
 0.54A 3bjwH-3dihA:
22.5		 3bjwH-3dihA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 5 PHE A   5
ILE A   9
GLY A  29
HIS A  47
 None
 0.53A 3r0lD-3dihA:
21.8		 3r0lD-3dihA:
53.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		5 / 9 VAL A  46
ALA A  92
PHE A  96
TYR A 103
TYR A  24
 None
 1.46A 4lb2B-3dihA:
undetectable		 4lb2B-3dihA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 3dih PHOSPHOLIPASE A2
HOMOLOG, AMMODYTIN L
(Vipera
ammodytes) 		4 / 8 PHE A   5
PHE A  96
VAL A  46
SER A  48
 None
 1.24A 6huoC-3dihA:
undetectable
6huoD-3dihA:
undetectable		 6huoC-3dihA:
21.49
6huoD-3dihA:
18.40