SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 7 LEU A 428
SER A 426
LEU A 430
ALA A 444
 None
 0.86A 1j8uA-3djaA:
undetectable		 1j8uA-3djaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 6 ARG A 204
GLY A 145
ASP A 146
TYR A 577
 None
 1.48A 1kf6M-3djaA:
undetectable
1kf6N-3djaA:
undetectable		 1kf6M-3djaA:
22.19
1kf6N-3djaA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 ASN A 423
LEU A 441
ASP A 440
GLU A 445
 None
 1.00A 1mxgA-3djaA:
undetectable		 1mxgA-3djaA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 VAL A 483
TRP A 349
PHE A 352
GLU A 350
 None
 1.49A 1om5A-3djaA:
undetectable
1om5B-3djaA:
undetectable		 1om5A-3djaA:
21.19
1om5B-3djaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 LEU A 417
MET A 434
GLY A 436
TYR A 437
HIS A 480
 None
 1.20A 1qabF-3djaA:
undetectable		 1qabF-3djaA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 TRP A 349
PHE A 352
GLU A 350
VAL A 483
 None
 1.44A 1rs6A-3djaA:
undetectable
1rs6B-3djaA:
3.2		 1rs6A-3djaA:
21.19
1rs6B-3djaA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 VAL A 483
TRP A 349
PHE A 352
GLU A 350
 None
 1.49A 2g6hA-3djaA:
undetectable
2g6hB-3djaA:
undetectable		 2g6hA-3djaA:
20.27
2g6hB-3djaA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 10 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.06A 2w3aB-3djaA:
undetectable		 2w3aB-3djaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.08A 2w3bA-3djaA:
undetectable		 2w3bA-3djaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 193
SER A  88
SER A  86
GLY A 222
ALA A 112
 None
 1.10A 2x2iA-3djaA:
undetectable		 2x2iA-3djaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 10 VAL A 193
SER A  88
SER A  86
GLY A 222
ALA A 112
 None
 1.04A 2x2iB-3djaA:
undetectable		 2x2iB-3djaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 193
SER A  88
SER A  86
GLY A 222
ALA A 112
 None
 1.13A 2x2iC-3djaA:
undetectable		 2x2iC-3djaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 528
CYH A 542
SER A 543
LEU A 544
THR A 545
 None
 0.79A 3a35A-3djaA:
undetectable		 3a35A-3djaA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 528
CYH A 542
SER A 543
LEU A 544
THR A 545
 None
 0.77A 3a35B-3djaA:
undetectable		 3a35B-3djaA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 528
CYH A 542
SER A 543
LEU A 544
THR A 545
 None
 0.76A 3a3bA-3djaA:
undetectable		 3a3bA-3djaA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 TRP A 349
PHE A 352
GLU A 350
VAL A 483
 None
 1.39A 3b3pA-3djaA:
undetectable
3b3pB-3djaA:
undetectable		 3b3pA-3djaA:
20.24
3b3pB-3djaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 GLY A 292
PHE A 293
ILE A 297
PHE A 570
 None
 0.93A 3ko0O-3djaA:
undetectable
3ko0Q-3djaA:
undetectable		 3ko0O-3djaA:
11.59
3ko0Q-3djaA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 GLY A 292
PHE A 293
ILE A 367
PHE A 570
 None
 0.97A 3ko0O-3djaA:
undetectable
3ko0Q-3djaA:
undetectable		 3ko0O-3djaA:
11.59
3ko0Q-3djaA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 6 GLY A 375
GLY A 376
SER A 499
HIS A 105
 None
 0.79A 3o9mB-3djaA:
2.1		 3o9mB-3djaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 528
ILE A  98
ASP A 103
THR A 109
LEU A 189
 None
 1.08A 3qfxA-3djaA:
undetectable		 3qfxA-3djaA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 VAL A 528
ILE A  98
ASP A 103
THR A 109
LEU A 189
 None
 1.07A 3qfxB-3djaA:
undetectable		 3qfxB-3djaA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		3 / 3 LYS A 397
SER A 449
GLN A 453
 None
 1.17A 3si7A-3djaA:
1.8		 3si7A-3djaA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		3 / 3 GLN A 123
PHE A 570
TYR A 580
 None
 0.90A 3ucjB-3djaA:
undetectable		 3ucjB-3djaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		3 / 3 GLN A 123
PHE A 570
TYR A 580
 None
 0.93A 3ucjA-3djaA:
undetectable		 3ucjA-3djaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 9 GLY A 523
ALA A 549
GLY A 525
VAL A 506
HIS A 398
 None
 1.50A 4c5lB-3djaA:
4.4		 4c5lB-3djaA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 GLY A 375
GLY A 376
SER A 334
SER A 499
HIS A 105
 None
 0.87A 4ey6A-3djaA:
undetectable		 4ey6A-3djaA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.07A 4kebB-3djaA:
undetectable		 4kebB-3djaA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.07A 4m6kA-3djaA:
undetectable		 4m6kA-3djaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 THR A 438
ASP A 432
ILE A 477
ASN A 433
LEU A 379
 None
 1.27A 4pooA-3djaA:
undetectable		 4pooA-3djaA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 LEU A 430
VAL A 420
TRP A 413
LEU A 416
 None
 1.10A 4pwdC-3djaA:
undetectable		 4pwdC-3djaA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.07A 4qlgB-3djaA:
undetectable		 4qlgB-3djaA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 8 TRP A 349
PHE A 352
GLU A 350
VAL A 483
 None
 1.43A 4uchA-3djaA:
undetectable
4uchB-3djaA:
undetectable		 4uchA-3djaA:
21.06
4uchB-3djaA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 GLU A 558
ALA A 172
ALA A 522
PHE A 104
GLY A 525
 None
 0.92A 4v04B-3djaA:
undetectable		 4v04B-3djaA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 7 TRP A 349
PHE A 352
GLU A 350
VAL A 483
 None
 1.41A 4v3wA-3djaA:
3.1
4v3wB-3djaA:
undetectable		 4v3wA-3djaA:
20.24
4v3wB-3djaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.06A 4x5fA-3djaA:
undetectable		 4x5fA-3djaA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 1.08A 4x5fB-3djaA:
undetectable		 4x5fB-3djaA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 11 THR A 171
ALA A 106
ASP A 502
THR A 521
GLY A 561
 None
 1.38A 4zjoD-3djaA:
2.4		 4zjoD-3djaA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 6 LEU A  43
LEU A  49
PHE A  97
LEU A  68
 None
 0.80A 5gs4A-3djaA:
undetectable		 5gs4A-3djaA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 6 CYH A 542
LEU A 544
HIS A  48
LEU A  50
 None
 1.17A 5hpuC-3djaA:
undetectable
5hpuD-3djaA:
undetectable		 5hpuC-3djaA:
2.46
5hpuD-3djaA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 GLY A 284
SER A 125
ILE A 575
PHE A 570
TYR A 580
 None
 1.38A 5igwA-3djaA:
undetectable		 5igwA-3djaA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		4 / 7 VAL A 483
TRP A 349
PHE A 352
GLU A 350
 None
 1.45A 6auuA-3djaA:
3.4
6auuB-3djaA:
undetectable		 6auuA-3djaA:
8.75
6auuB-3djaA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 11 GLY A 376
SER A 499
ALA A 501
ASN A 530
VAL A 528
 None
 1.32A 6hu9A-3djaA:
undetectable
6hu9E-3djaA:
0.8
6hu9I-3djaA:
undetectable		 6hu9A-3djaA:
22.73
6hu9E-3djaA:
15.74
6hu9I-3djaA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3dja PROTEIN CT_858
(Chlamydia
trachomatis) 		5 / 12 ILE A 557
PHE A 503
THR A 545
LEU A 471
THR A 521
 None
 0.99A 7dfrA-3djaA:
undetectable		 7dfrA-3djaA:
14.19