SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3djd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 182
THR A 180
PRO A  38
 None
None
FAD  A 500 (-4.3A)
 0.84A 1fjaC-3djdA:
undetectable		 1fjaC-3djdA:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 182
THR A 180
PRO A  38
 None
None
FAD  A 500 (-4.3A)
 0.84A 1fjaD-3djdA:
undetectable		 1fjaD-3djdA:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 THR A 234
PRO A 233
ARG A 403
THR A 340
GLY A 361
 None
 1.19A 1h4oC-3djdA:
undetectable
1h4oD-3djdA:
undetectable		 1h4oC-3djdA:
17.62
1h4oD-3djdA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 THR A 234
PRO A 233
ARG A 403
THR A 340
GLY A 361
 None
 1.17A 1h4oE-3djdA:
undetectable
1h4oF-3djdA:
undetectable		 1h4oE-3djdA:
17.62
1h4oF-3djdA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 182
THR A 180
PRO A  38
 None
None
FAD  A 500 (-4.3A)
 0.85A 209dC-3djdA:
undetectable		 209dC-3djdA:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 6 ARG A 333
SER A  43
GLY A  15
THR A  16
 None
FAD  A 500 (-2.9A)
FAD  A 500 (-3.2A)
FAD  A 500 (-3.2A)
 1.22A 2f7fA-3djdA:
undetectable		 2f7fA-3djdA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 392
GLU A 344
LEU A  73
ILE A 377
GLY A 359
 None
 1.25A 2j7xA-3djdA:
undetectable		 2j7xA-3djdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 6 ASP A 279
VAL A 313
PRO A 306
THR A 428
 None
 1.42A 2q6oB-3djdA:
undetectable		 2q6oB-3djdA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 THR A 234
PRO A 233
ARG A 403
THR A 340
GLY A 361
 None
 1.16A 2vl2A-3djdA:
undetectable
2vl2C-3djdA:
undetectable		 2vl2A-3djdA:
17.81
2vl2C-3djdA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 358
VAL A  12
GLY A  13
ARG A 186
LEU A 225
 None
FAD  A 500 ( 4.5A)
FAD  A 500 (-3.5A)
FAD  A 500 ( 4.4A)
None
 1.01A 3ijdB-3djdA:
undetectable		 3ijdB-3djdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 164
VAL A  41
LEU A  86
GLU A 170
ALA A  22
 None
 0.99A 3mdvB-3djdA:
undetectable		 3mdvB-3djdA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 5 GLU A 247
LEU A 250
GLN A 323
GLY A 137
 None
 1.25A 3pp1A-3djdA:
undetectable		 3pp1A-3djdA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 4 VAL A  51
PHE A 331
PHE A 329
VAL A 313
 None
 1.27A 3rv5C-3djdA:
undetectable
3rv5D-3djdA:
undetectable		 3rv5C-3djdA:
12.16
3rv5D-3djdA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 ASN A 229
TRP A 405
ASP A 226
 None
 0.89A 4a7tA-3djdA:
undetectable
4a7tF-3djdA:
undetectable		 4a7tA-3djdA:
17.21
4a7tF-3djdA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 8 GLN A 431
LYS A 307
ASN A 429
THR A 428
 None
 1.27A 4d1yA-3djdA:
undetectable
4d1yB-3djdA:
undetectable		 4d1yA-3djdA:
17.69
4d1yB-3djdA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 392
GLU A 344
LEU A  73
ILE A 377
GLY A 359
 None
 1.26A 4j26A-3djdA:
undetectable		 4j26A-3djdA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 GLU A 310
ARG A 314
GLN A 304
 None
 0.91A 4rtbA-3djdA:
undetectable		 4rtbA-3djdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 167
LEU A  86
ARG A 173
HIS A 159
LEU A 370
 None
 1.09A 4zn7A-3djdA:
undetectable		 4zn7A-3djdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 GLY A  13
GLY A  15
THR A  21
ASP A  37
PRO A  38
 FAD  A 500 (-3.5A)
FAD  A 500 (-3.2A)
None
FAD  A 500 (-2.7A)
FAD  A 500 (-4.3A)
 1.19A 5bw4A-3djdA:
undetectable		 5bw4A-3djdA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 VAL A 179
PHE A 178
ILE A  11
LEU A 356
ALA A 221
 None
 1.33A 5fctB-3djdA:
undetectable		 5fctB-3djdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 4 CYH A 216
PHE A 214
ILE A 393
GLY A 374
 None
 1.40A 5hesB-3djdA:
undetectable		 5hesB-3djdA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 GLY A  48
HIS A 159
GLU A 267
ALA A 166
ILE A  55
 FAD  A 500 (-3.9A)
None
None
None
None
 1.20A 5igvA-3djdA:
undetectable		 5igvA-3djdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 7 GLY A 105
GLU A 261
ARG A 411
ASP A 107
 None
 1.10A 5n5dB-3djdA:
2.1		 5n5dB-3djdA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 7 THR A 234
ILE A 334
THR A 237
PHE A 421
 None
 1.02A 5zsfA-3djdA:
undetectable
5zsfB-3djdA:
undetectable		 5zsfA-3djdA:
9.79
5zsfB-3djdA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 VAL A 424
PHE A 421
THR A 234
ILE A 334
THR A 237
 None
 1.08A 5zsfA-3djdA:
0.0
5zsfB-3djdA:
0.0		 5zsfA-3djdA:
9.79
5zsfB-3djdA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 163
ALA A  14
ALA A 168
ALA A 171
PHE A 178
 None
 0.97A 5zw4A-3djdA:
2.6		 5zw4A-3djdA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ALA A  26
VAL A  33
GLY A 374
LEU A   9
VAL A 176
 None
 0.89A 6dh0B-3djdA:
undetectable		 6dh0B-3djdA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 435
GLY A  48
ALA A  47
PHE A 367
LEU A 238
 None
FAD  A 500 (-3.9A)
FAD  A 500 (-3.2A)
None
None
 1.11A 6dwnD-3djdA:
undetectable		 6dwnD-3djdA:
10.84