SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3djl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3djl PROTEIN AIDB
(Escherichia
coli) 		3 / 3 TRP A 279
TYR A 208
LEU A 210
 None
 0.92A 1kxhA-3djlA:
undetectable		 1kxhA-3djlA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 LEU A 492
ALA A 380
VAL A 438
ARG A 375
LEU A 474
 None
 1.14A 1s9pB-3djlA:
undetectable		 1s9pB-3djlA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 LEU A 348
LEU A 532
MET A 506
LEU A 523
THR A 352
 None
 1.45A 1ya3A-3djlA:
undetectable		 1ya3A-3djlA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3djl PROTEIN AIDB
(Escherichia
coli) 		3 / 3 THR A 136
PRO A 134
THR A 138
 None
 0.62A 209dC-3djlA:
undetectable		 209dC-3djlA:
1.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 7 ALA A 224
GLY A 278
ILE A 277
PRO A 152
 None
 0.57A 2fxdB-3djlA:
undetectable		 2fxdB-3djlA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 7 ALA A 317
GLY A 401
ILE A 403
PRO A 412
 None
 0.84A 2fxdB-3djlA:
undetectable		 2fxdB-3djlA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 5 LEU A 160
PRO A 159
LEU A 178
ILE A 180
 None
 0.83A 2qd4A-3djlA:
undetectable		 2qd4A-3djlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 8 ALA A 224
GLY A 278
ILE A 277
PRO A 152
 None
 0.69A 3el9A-3djlA:
undetectable		 3el9A-3djlA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 GLY A 206
LEU A 203
ILE A 277
LEU A 244
ASP A 246
 None
 0.86A 3gwvA-3djlA:
undetectable		 3gwvA-3djlA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 5 ASN A 250
ALA A 276
ALA A 251
ARG A 253
 None
 1.37A 3kp2B-3djlA:
undetectable		 3kp2B-3djlA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 8 ALA A 224
GLY A 278
ILE A 277
PRO A 152
 None
 0.71A 3nu9A-3djlA:
undetectable		 3nu9A-3djlA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 7 ILE A 318
ILE A 332
LEU A 341
SER A 342
 None
 0.66A 3r9vA-3djlA:
1.7
3r9vB-3djlA:
1.1		 3r9vA-3djlA:
18.62
3r9vB-3djlA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 6 LEU A 414
PRO A 412
GLU A 410
SER A 409
 None
 1.06A 3vlnA-3djlA:
2.1		 3vlnA-3djlA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 11 LEU A 439
VAL A 445
PHE A 377
ALA A 452
PHE A 453
 None
 1.48A 4evrA-3djlA:
undetectable		 4evrA-3djlA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 4 LEU A 160
PRO A 159
LEU A 178
ILE A 180
 None
 0.92A 4f4dB-3djlA:
undetectable		 4f4dB-3djlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 GLY A 305
ALA A 125
ALA A 119
VAL A  31
GLN A 126
 None
 1.44A 4ryaA-3djlA:
undetectable		 4ryaA-3djlA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 10 PHE A 114
GLY A 305
LEU A 123
ALA A 119
ALA A 359
 None
 1.33A 4wnuD-3djlA:
undetectable		 4wnuD-3djlA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 LEU A  56
GLY A 130
PRO A 134
ASN A  63
ARG A 312
 None
 1.31A 4x61A-3djlA:
undetectable		 4x61A-3djlA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 LEU A  56
GLY A 130
PRO A 134
ASN A  63
ARG A 312
 None
 1.23A 5emlA-3djlA:
undetectable		 5emlA-3djlA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 12 VAL A  82
ASP A  81
ALA A 267
ARG A 242
LEU A 179
 None
 1.10A 5m5cB-3djlA:
undetectable		 5m5cB-3djlA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 10 ALA A  53
LEU A  56
GLY A  59
ILE A 318
LEU A 341
 None
 1.22A 5oy01-3djlA:
2.4
5oy07-3djlA:
undetectable		 5oy01-3djlA:
9.51
5oy07-3djlA:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 8 THR A 298
THR A 378
ARG A 375
TRP A 362
 None
 1.38A 5tzoA-3djlA:
undetectable		 5tzoA-3djlA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 8 THR A 298
THR A 378
ARG A 375
TRP A 362
 None
 1.39A 5tzoB-3djlA:
undetectable		 5tzoB-3djlA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 8 THR A 298
THR A 378
ARG A 375
TRP A 362
 None
 1.40A 5tzoC-3djlA:
undetectable		 5tzoC-3djlA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3djl PROTEIN AIDB
(Escherichia
coli) 		3 / 3 GLY A 295
VAL A 193
MET A 184
 None
None
FAD  A 602 (-4.2A)
 0.62A 5ycpA-3djlA:
undetectable		 5ycpA-3djlA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3djl PROTEIN AIDB
(Escherichia
coli) 		4 / 4 VAL A  31
GLY A  37
ASP A  39
ASP A  41
 None
 1.16A 6cjkC-3djlA:
undetectable		 6cjkC-3djlA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 3djl PROTEIN AIDB
(Escherichia
coli) 		5 / 11 ASN A  17
GLY A 537
PRO A  14
LEU A  56
GLN A 126
 None
 1.14A 6euqA-3djlA:
2.0		 6euqA-3djlA:
23.70