SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dkt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		4 / 6 PHE A  85
VAL A 245
ALA A  12
LEU A  14
 None
 0.77A 1e7bB-3dktA:
undetectable		 1e7bB-3dktA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		4 / 6 VAL A 257
GLU A 261
ARG A 140
PHE A 137
 None
 1.08A 1s8fB-3dktA:
undetectable		 1s8fB-3dktA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		4 / 6 LEU A 134
PHE A 255
LEU A 227
ASP A 224
 None
 1.10A 2wm3A-3dktA:
undetectable		 2wm3A-3dktA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		5 / 10 GLY A 169
ILE A 264
PHE A 123
PHE A 225
PHE A  39
 None
 1.47A 3ko0R-3dktA:
undetectable
3ko0T-3dktA:
undetectable		 3ko0R-3dktA:
18.87
3ko0T-3dktA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		4 / 6 ARG A  27
ILE A  29
VAL A 111
LEU A 107
 None
 1.02A 4em2A-3dktA:
undetectable		 4em2A-3dktA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		4 / 7 PHE A 255
PRO A 260
GLN A 256
PHE A 137
 None
 1.44A 4grqA-3dktA:
undetectable
4grqC-3dktA:
undetectable		 4grqA-3dktA:
18.92
4grqC-3dktA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		5 / 12 LEU A 266
ALA A 154
ILE A 175
ALA A 215
ILE A 206
 None
 0.91A 4o2bD-3dktA:
undetectable		 4o2bD-3dktA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		5 / 12 ALA A 154
LEU A 266
PHE A 183
LEU A 193
ILE A 155
 None
 1.09A 5m24A-3dktA:
undetectable		 5m24A-3dktA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		5 / 12 GLY A 133
SER A 136
ASN A 259
GLU A 261
LEU A 263
 None
 1.21A 5nwuA-3dktA:
undetectable		 5nwuA-3dktA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3dkt MARITIMACIN
(Thermotoga
maritima) 		5 / 12 THR A 110
VAL A 111
VAL A 114
SER A 105
GLU A  91
 None
 1.12A 6bzoC-3dktA:
undetectable		 6bzoC-3dktA:
12.72