SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dkw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GV1_B_BEZB303_0 (DISULFIDE INTERCHANGE PROTEIN)	3dkw	DNR PROTEIN (Pseudomonas aeruginosa)	4 / 4	LEU A 56 ALA A 102 VAL A 103 PRO A 105	None	1.18A	3gv1B-3dkwA: undetectable	3gv1B-3dkwA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GV1_B_BEZB303_0 (DISULFIDE INTERCHANGE PROTEIN)	3dkw	DNR PROTEIN (Pseudomonas aeruginosa)	4 / 4	LEU A 108 ALA A 102 VAL A 103 PRO A 105	None	1.24A	3gv1B-3dkwA: undetectable	3gv1B-3dkwA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_A_RTLA201_1 (RETINOL-BINDING PROTEIN 2)	3dkw	DNR PROTEIN (Pseudomonas aeruginosa)	3 / 3	PHE A 90 THR A 78 LEU A 16	None	0.73A	4qztA-3dkwA: undetectable	4qztA-3dkwA: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GS4_A_ESTA603_2 (ESTROGEN RECEPTOR)	3dkw	DNR PROTEIN (Pseudomonas aeruginosa)	4 / 6	LEU A 120 LEU A 117 PHE A 53 LEU A 28	None	0.84A	5gs4A-3dkwA: undetectable	5gs4A-3dkwA: 24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YK2_A_ERYA501_0 (PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER)	3dkw	DNR PROTEIN (Pseudomonas aeruginosa)	5 / 11	ALA A 185 PRO A 192 ILE A 190 ARG A 156 VAL A 157	None	1.12A	5yk2A-3dkwA: undetectable	5yk2A-3dkwA: 19.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GV1_B_BEZB303_0","DISULFIDE INTERCHANGE PROTEIN","3dkw","DNR PROTEIN","Pseudomonas aeruginosa",4,"LEU A  56;ALA A 102;VAL A 103;PRO A 105","None","1.18A","3gv1B-3dkwA:undetectable","3gv1B-3dkwA:19.58"],["3GV1_B_BEZB303_0","DISULFIDE INTERCHANGE PROTEIN","3dkw","DNR PROTEIN","Pseudomonas aeruginosa",4,"LEU A 108;ALA A 102;VAL A 103;PRO A 105","None","1.24A","3gv1B-3dkwA:undetectable","3gv1B-3dkwA:19.58"],["4QZT_A_RTLA201_1","RETINOL-BINDING PROTEIN 2","3dkw","DNR PROTEIN","Pseudomonas aeruginosa",3,"PHE A  90;THR A  78;LEU A  16","None","0.73A","4qztA-3dkwA:undetectable","4qztA-3dkwA:19.40"],["5GS4_A_ESTA603_2","ESTROGEN RECEPTOR","3dkw","DNR PROTEIN","Pseudomonas aeruginosa",4,"LEU A 120;LEU A 117;PHE A  53;LEU A  28","None","0.84A","5gs4A-3dkwA:undetectable","5gs4A-3dkwA:24.44"],["5YK2_A_ERYA501_0","PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER","3dkw","DNR PROTEIN","Pseudomonas aeruginosa",5,"ALA A 185;PRO A 192;ILE A 190;ARG A 156;VAL A 157","None","1.12A","5yk2A-3dkwA:undetectable","5yk2A-3dkwA:19.20"]]